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Cat. No.: HY-117383R

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NGI-1 (Standard)

Name: NGI-1 (Standard)
Brand: MedChemExpress
SKU: HY-117383R
Availability: PreOrder

(Synonyms: ML414 (Standard))

NGI-1 (Standard) is the analytical standard of NGI-1 (HY-117383). This product is intended for research and analytical applications. NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocK_ing the function of the OST catalytic subunits STT3A and STT3B. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability.

For research use only. We do not sell to patients.

CAS No.: 790702-57-7
Formula: C₁₇H₂₂N₄O₃S₂
Molecular Weight:394.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NGI-1 (Standard) Chemical Structure

CAS No.: 790702-57-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 790702-57-7
Molecular Weight 394.51
Formula C₁₇H₂₂N₄O₃S₂
SMILES

O=C(NC1=NC=C(C)S1)C2=CC(S(=O)(N(C)C)=O)=CC=C2N3CCCC3
Synonyms

ML414 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhu S, et al. Comprehensive Interactome Analysis Reveals that STT3B is Required for the N-Glycosylation of Lassa Virus Glycoprotein. J Virol. 2019 Sep 11. pii: JVI.01443-19. [Content Brief]

[2]. Lopez-Sambrooks C, et al. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol. 2016 Dec;12(12):1023-1030. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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