1. Immunology/Inflammation
  2. NOD-like Receptor (NLR)
  3. NLRP3-IN-18

NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC50 value of ≤1.0 µM.

For research use only. We do not sell to patients.

NLRP3-IN-18 Chemical Structure

NLRP3-IN-18 Chemical Structure

CAS No. : 2769040-06-2

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Based on 1 publication(s) in Google Scholar

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Description

NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC50 value of ≤1.0 µM[1].

IC50 & Target[1]

NLRP3

≤1.0 μM (IC50)

Molecular Weight

339.82

Formula

C19H18ClN3O

CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

ClC(C=C1)=CC=C1C2=NN=C(C3=C2C=CC=C3)NC[C@@H]4CCCO4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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NLRP3-IN-18 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NLRP3-IN-18
Cat. No.:
HY-153554
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