NLRP3-IN-78
NLRP3-IN-78 (compound 21) is a NLRP3 inhibitor with the inhibition rate of 46.72% in GSDMD-induced pyroptosis at 5 μM. NLRP3-IN-78 binds to the NLRP3 protein and inhibits GSDMD-NT oligomerization. NLRP3-IN-78 also inhibits GSDMD cleavage, and upstream NF-κB signaling, demonstrating its anti-inflammatory activity.
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- No. CAS: 477546-27-3
- Fòrmula: C12H5Cl2N3O4S2
- Peso molecular:390.22
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 477546-27-3
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Peso molecular 390.22
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Fòrmula C12H5Cl2N3O4S2
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SMILES
ClC1=CC(C2=CSC(NC(C3=CC=C([N+]([O-])=O)O3)=O)=N2)=C(Cl)S1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3-IN-78 Related Classifications
HY-172788 Related Classifications
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