NLRP3-IN-88
NLRP3-IN-88 (Compound 1) is an NLRP3 inhibitor. NLRP3-IN-88 inhibits IL-1β. NLRP3-IN-88 can be used in research on intestinal diseases and inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 2557349-73-0
- Formula: C18H21F3N4O
- Molecular Weight:366.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-1β |
NLRP3 |
NLRP3-IN-88 (10 doses starting from 5 μΜ; 3 h) inhibits IL-1β in THP-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2557349-73-0
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Molecular Weight 366.38
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Formula C18H21F3N4O
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SMILES
OC1=C(C2=C(C=C(N=N2)N[C@H]3CN(CCC3)C)C)C=CC(C(F)(F)F)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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