NLRP3-IN-NBC6

NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor (IC50= 574 nM) that acts independently of Ca2+. NLRP3-IN-NBC6 inhibits Nigericin (HY-127019)-induced inflammasome activation in THP-1 cells and Imiquimod (HY-B0180)-induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).

For research use only. We do not sell to patients.

  • CAS No.: 2068818-02-8
  • Formula: C18H16BCl3N2O2
  • Molecular Weight:409.50
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
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  • Chemical Information
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All NOD-like Receptor (NLR) Isoforms

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