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Cat. No.: HY-W778236

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Norflurazon-¹³C,d₃

Name: Norflurazon-13C,d3
Brand: MedChemExpress
SKU: HY-W778236
Price: 392.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: SAN 9789-¹³C,d₃)

Norflurazon-¹³C,d₃ (SAN 9789-¹³C,d₃) is the d₃, ¹³C-labeled Norflurazon (HY-114849). Norflurazon (SAN 9789) is a pre-emergence Herbicide. Norflurazon non-competitively inhibits phytoene desaturase by competing with the enzyme cofactor and disrupts carotenoid biosynthesis, thereby leading to chlorophyll photodegradation and chlorosis. Norflurazon inhibits MGDG synthase, CDP-choline phosphotransferase, Omega-3 FAD7 desaturase, and PG delta-3-trans desaturase, and activates LysoPC-acyltransferase and Omega-3 FAD3 desaturase. Norflurazon inhibits photosynthetic membrane organization, mitochondrial respiration, ATP production, PI3K signaling, and ERK1/2 phosphorylation. Norflurazon activates MAPK P38 phosphorylation and ER stress signaling. Norflurazon induces morphological malformations and cardiovascular effects in zebrafish embryos.

For research use only. We do not sell to patients.

CAS No.: 1346603-47-1
Formula: C₁₁¹³CH₆D₃ClF₃N₃O
Molecular Weight:307.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Norflurazon-¹³C,d₃ Chemical Structure

CAS No.: 1346603-47-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

IC₅₀ & Target

^[4]

ERK1

ERK2

All PI3K Isoforms :

All ERK Isoforms :

All p38 MAPK Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1346603-47-1
Unlabeled CAS 27314-13-2
Molecular Weight 307.68
Formula C₁₁¹³CH₆D₃ClF₃N₃O
SMILES

ClC1=C(C=NN(C1=O)C2=CC=CC(C(F)(F)F)=C2)N[13C]([2H])([2H])[2H]
Synonyms

SAN 9789-¹³C,d₃
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Abrous-Belbachir O, et al. Evidence that norflurazon affects chloroplast lipid unsaturation in soybean leaves (Glycine max L.). Journal of agricultural and food chemistry. 2009 Dec 09;57(23):11434-40. [Content Brief]

[2]. Leetanasaksakul K, et al. Proteomic analysis of differential responses to norflurazon herbicide in the model green alga Chlamydomonas reinhardtii. Scientific reports. 2025 Aug 27;15(1):31601.

[3]. Niemann L, et al. First draft prepared by Lars Niemann1 and Alan Boobis2 Department of Pesticides Safety, German Federal Institute for Risk Assessment, Berlin, Germany 2 Department of Medicine, Imperial College London, London, United Kingdom[J].

[4]. Hong T, et al. Norflurazon causes cell death and inhibits implantation-related genes in porcine trophectoderm and uterine luminal epithelial cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Apr;186:114559.

[5]. An G, et al. Norflurazon causes developmental defects including cardiovascular abnormalities in early-stage zebrafish (Danio rerio)[J]. Journal of Animal Reproduction and Biotechnology, 2022, 37(3): 176-182.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References

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Norflurazon-¹³C,d₃

All PI3K Isoforms

All ERK Isoforms

All p38 MAPK Isoforms