2. NF-κB
  3. Keap1-Nrf2
  4. Nrf2 activator-1

Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1).

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Nrf2 activator-1

Nrf2 activator-1 構造式

CAS 番号 : 2230697-41-1

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 621 在庫あり
Solution
10 mM * 1 mL in DMSO USD 621 在庫あり
Solid
5 mg $488 在庫あり
10 mg $780 在庫あり
25 mg $1400 在庫あり
50 mg $2100 在庫あり
100 mg $2940 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Nrf2 activator-1 関連抗体

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製品説明

Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1)[1].

IC50 & Target

Nrf2[1]
分子量

578.68

分子式

C30H34N4O6S
CAS 番号
Appearance

Solid

Color

White to yellow

SMILES

CCOC(C[C@@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (172.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7281 mL 8.6404 mL 17.2807 mL
5 mM 0.3456 mL 1.7281 mL 3.4561 mL
10 mM 0.1728 mL 0.8640 mL 1.7281 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7281 mL 8.6404 mL 17.2807 mL 43.2018 mL
5 mM 0.3456 mL 1.7281 mL 3.4561 mL 8.6404 mL
10 mM 0.1728 mL 0.8640 mL 1.7281 mL 4.3202 mL
15 mM 0.1152 mL 0.5760 mL 1.1520 mL 2.8801 mL
20 mM 0.0864 mL 0.4320 mL 0.8640 mL 2.1601 mL
25 mM 0.0691 mL 0.3456 mL 0.6912 mL 1.7281 mL
30 mM 0.0576 mL 0.2880 mL 0.5760 mL 1.4401 mL
40 mM 0.0432 mL 0.2160 mL 0.4320 mL 1.0800 mL
50 mM 0.0346 mL 0.1728 mL 0.3456 mL 0.8640 mL
60 mM 0.0288 mL 0.1440 mL 0.2880 mL 0.7200 mL
80 mM 0.0216 mL 0.1080 mL 0.2160 mL 0.5400 mL
100 mM 0.0173 mL 0.0864 mL 0.1728 mL 0.4320 mL
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Nrf2 activator-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nrf2 activator-12230697-41-1Keap1-Nrf2Nrf2activatorCOPDasthmaALIARDSpulmonary fibrosisInhibitorinhibitorinhibit

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製品名:
Nrf2 activator-1
製品番号:
HY-145390
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