1. Epigenetics
  2. Histone Acetyltransferase
  3. NSC 694621

NSC 694621 

Cat. No.: HY-147288
Handling Instructions

NSC 694621 is a potent PCAF inhibitor, with IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells.

For research use only. We do not sell to patients.

NSC 694621 Chemical Structure

NSC 694621 Chemical Structure

CAS No. : 104857-29-6

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Description

NSC 694621 is a potent PCAF inhibitor, with IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].

IC50 & Target

IC50: 5.71 µM (PCAF/H31-21)[1].

In Vitro

NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: SK-N-SH, HCT116 cells
Concentration: 25 µM
Incubation Time: 72 h
Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 19.2 µM and growth inhibition of 29%, respectively.
Molecular Weight

258.30

Formula

C13H10N2O2S

CAS No.
SMILES

O=C1C2=CC=CN=C2SN1C3=CC=C(C=C3)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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NSC 694621
Cat. No.:
HY-147288
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