PBPE hydrochloride (Standard)
PBPE hydrochloride (Standard) is the analytical standard of PBPE (hydrochloride) (HY-10830A). This product is intended for research and analytical applications. PBPE hydrochloride is a derivative of tamoxifen (HY-13757A) and a selective ligand for the anti-estrogen binding site (AEBS), the binding affinities (Ki) of PBPE hydrochloride and MBPE to AEBS are 8.79 and 17.57 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 262425-59-2
- Formula: C19H24ClNO
- Molecular Weight:317.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 262425-59-2
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Molecular Weight 317.85
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Formula C19H24ClNO
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SMILES
C1(OCCN2CCCC2)=CC=C(CC3=CC=CC=C3)C=C1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. B Kedjouar, et al. Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor. Biochem Pharmacol. 1999 Dec 15;58(12):1927-39. [Content Brief]
[2]. Florence Dalenc, et al. Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways. Breast Cancer Res. 2005;7(6):R1159-67. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PBPE hydrochloride (Standard) Related Classifications
HY-10830AR Related Classifications
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