Peimine (Standard)
Peimine (Standard) is the analytical standard of Peimine. This product is intended for research and analytical applications. Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research.
For research use only. We do not sell to patients.
- CAS No.: 23496-41-5
- Formula: C27H45NO3
- Molecular Weight:431.65
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 23496-41-5
-
Molecular Weight 431.65
-
Formula C27H45NO3
-
SMILES
[H][C@]12[C@]3([H])C[C@H](O)[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])C[C@]([H])1[C@]5([H])CN6C[C@@H](C)CC[C@]([H])6[C@@](C)(O)[C@]([H])5CC2
-
Synonyms
Verticine (Standard); Dihydroisoimperialine (Standard)
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yi PF, et al. Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 macrophages. Immunopharmacol Immunotoxicol. 2013 Oct;35(5):567-72. [Content Brief]
[2]. Chen K, Lv ZT, Zhou CH, et al. Peimine suppresses interleukin‑1β‑induced inflammation via MAPK downregulation in chondrocytes. Int J Mol Med. 2019;43(5):2241-2251. [Content Brief]
[3]. Tan H, et al. Peimine inhibits the growth and motility of prostate cancer cells and induces apoptosis by disruption of intracellular calcium homeostasis through Ca2+ /CaMKII/JNK pathway. J Cell Biochem. 2020 Jan;121(1):81-92. [Content Brief]
[4]. Liu C, et al. Synergistic anti-inflammatory effects of peimine, peiminine, and forsythoside a combination on LPS-induced acute lung injury by inhibition of the IL-17-NF-κB/MAPK pathway activation. J Ethnopharmacol. 2022 Sep 15;295:115343. [Content Brief]
[5]. Chen LH, et al. Sex dependent pharmacokinetics, tissue distribution and excretion of peimine and peiminine in rats assessed by liquid chromatography-tandem mass spectrometry. J Ethnopharmacol. 2013 Jan 9;145(1):77-84. [Content Brief]
[6]. Yi PF, et al. Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 macrophages. Immunopharmacol Immunotoxicol. 2013 Oct;35(5):567-72. [Content Brief]
[7]. Xu J, et al. Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level. Fitoterapia. 2016 Jun;111:1-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Peimine (Standard) Related Classifications
HY-N0212R Related Classifications
Powered by Bioz
- Peimine (Standard)
- 23496-41-5
- Verticine (Standard)
- Dihydroisoimperialine (Standard)
- Reference Standards
- Apoptosis
- Interleukin Related
- TNF Receptor
- p38 MAPK
- NF-κB
- prostate cancer
- intracellular calcium homeostasis
- apoptosis
- LPS-induced acute lung injury in mice
- inflammatory
- Nav1.7 ion channel
- Kv1.3 ion channel
- Inhibitor
- inhibitor
- inhibit