- Peptides
- Peptide and Derivatives
- Antimicrobial Peptides
Antimicrobial Peptides
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Antimicrobial Peptides (681)
Gramicidin C is a naturally occuring polypeptide antibiotic isolated from B. brevis var. G.B.
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- Formula: C65H122F3N25O14
- Molecular Weight: 1534.85
Bac2A TFA is an antimicrobial and immunomodulatory peptide. Bac2A TFA is a linear variant of bactenecin and is very effective against fungal pathogens.
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- Formula: C147H217N43O37S6
- Molecular Weight: 3370.95
Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.
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- Formula: C180H313N59O50S9
- Molecular Weight: 4392.36
β-defesin 1 (pig) (pBD-1) is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs.
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- Formula: Magainin I (TFA) C112H177N29O28S·xC2HF3O2
- Molecular Weight: 2409.85 (free base)
Magainin 1 TFA (Magainin I TFA) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria.
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- Formula: C105H188N34O21
- Molecular Weight: 2262.83
OV-1, sheep is an alpha-helical antimicrobial ovispirin peptide derived from SMAP29 peptide (sheep), which inhibits several antibiotic-resistant bacterial strains including mucoid and nonmucoid Pseudomonas aeruginosa.
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- Formula: C50H85N19O14
- Molecular Weight: 1176.33
Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect.
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- Formula: C44H66N14O10S
- Molecular Weight: 983.15
Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect.
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- Formula: C109H156N22O25S2
- Molecular Weight: 2238.67
VIR-165 is a modified form of virus inhibitory peptide (VIRIP) that binds the fusion peptide of the gp41 subunit and prevents its insertion into the target membrane. VIRIP inhibits a wide variety of human immunodeficiency virus type 1 (HIV-1) strains.
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- Formula: C135H235N35O32
- Molecular Weight: 2860.53
Ceratotoxins B is antibacterial peptide produced by the sexually mature females of Ceratitis capitata. Lytic and antibacterial activity .
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- Formula: C97H173N51O24
- Molecular Weight: 2437.74
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- Formula: C115H194N34O33
- Molecular Weight: 2580.98
Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide from Bombina species.
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- Formula: C63H118N24O13S2
- Molecular Weight: 1483.89
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei.
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- Formula: C46H71N10NaO15S
- Molecular Weight: 1059.17
Reltecimod sodium (AB-103 sodium) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod sodium has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod sodium modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod sodium can be used to research necrotizing soft-tissue infections (NSTIs).
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- Formula: C56H91D7N16O13.5C2HF3O2
- Molecular Weight: 1780.64
Polymyxin B1-D-Leu-d7 TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment.
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- Formula: C56H71N9O20
- Molecular Weight: 1190.21
Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species.
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