1. Metabolic Enzyme/Protease
  2. Glucokinase
  3. PF-04937319

PF-04937319 

Cat. No.: HY-108328 Purity: 96.28%
Handling Instructions

PF-04937319 is a glucokinase activator (GKA) with EC50 value of 154.4  μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus. PF-04937319 is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs.

For research use only. We do not sell to patients.

PF-04937319 Chemical Structure

PF-04937319 Chemical Structure

CAS No. : 1245603-92-2

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1 mg USD 75 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

PF-04937319 is a glucokinase activator (GKA) with EC50 value of 154.4  μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus[1]. PF-04937319 is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs[2].

IC50 & Target

EC50: 154.4 μM (GSA) (PF-04937319)[1]

Molecular Weight

432.43

Formula

C₂₂H₂₀N₆O₄

CAS No.

1245603-92-2

SMILES

O=C(C1=NC=C(OC2=C3C=C(C)OC3=CC(C(NC4=NC=C(C)N=C4)=O)=C2)C=N1)N(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

PF-04937319PF04937319PF 04937319GlucokinaseHexokinase IVHexokinase DInhibitorinhibitorinhibit

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Product name:
PF-04937319
Cat. No.:
HY-108328
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