Pitstop 2 (Standard)
Pitstop 2 (Standard) is the analytical standard of Pitstop 2 (HY-115604). This product is intended for research and analytical applications. Pitstop 2 is a clathrin inhibitor which inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. Pitstop 2 has the potential for anti-cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1419320-73-2
- Formula: C20H13BrN2O3S2
- Molecular Weight:473.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1419320-73-2
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Molecular Weight 473.36
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Formula C20H13BrN2O3S2
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SMILES
O=S(C1=C2C=CC=CC2=CC=C1)(NC(S/C3=C\C4=CC=C(Br)C=C4)=NC3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kumar GA, et, al. Leishmania donovani Internalizes into Host Cells via Caveolin-mediated Endocytosis. Sci Rep. 2019 Sep 2; 9(1): 12636. [Content Brief]
[2]. Smith CM, et, al. Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells. Mol Cancer. 2013 Jan 17; 12:4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)