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PLK1-IN-9

PLK1-IN-9 (Compound M2) is an inhibitor for polo-like kinase 1 (PLK1), that inhibits PLK proteins modified with peptides 1010pT, cdc25c and PBIP, with IC50s of 1.6, 0.8 and 1.4 μM, respectively. PLK1-IN-9 inhibits proliferations of cancer cells HeLa, HL60, SNU387/499, HepG2, exhibits cytotoxicity and induces apoptosis. PLK1-IN-9 inhibits tumor growth in HepG2 xenograft mouse model.

For research use only. We do not sell to patients.

  • CAS No.: 893772-67-3
  • Formula: C12H7F3N4O2
  • Molecular Weight:296.20
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • PLK1-IN-9 Chemical Structure
    PLK1-IN-9 Chemical Structure
CAS No.: 893772-67-3
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609-228-6898
[email protected] [email protected]
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Top Publications Citing

Use of MCE Products

All Polo-like Kinase (PLK) Isoforms

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  • PLK1-IN-9 Chemical Structure
    PLK1-IN-9 Chemical Structure
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  • PLK1-IN-9