PMEG-DP disodium
PMEG-DP disodium is a potent DNA polymerase inhibitor (IC50=2.5 μM), especially for DNA polymerase α and δ. PMEG-DP disodium acts as an active metabolite of G-9191, which effectively inhibits the growth of papillomavirus (HPV) -infected cell lines. PMEG-DP disodium can be used in the study of HPV-related diseases.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C8H12N5Na2O11P3
- Molecular Weight:493.11
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
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DNA Polymerase |
Chemical Information
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Molecular Weight 493.11
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Formel C8H12N5Na2O11P3
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SMILES
O=C1N=C(NC2=C1N=CN2CCOCP(O)(OP(O)(OP(O[Na])(O[Na])=O)=O)=O)N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Wolfgang G H I, et al. GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl) guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions[J]. Antimicrobial agents and chemotherapy, 2009, 53(7): 2777-2784. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PMEG-DP disodium Related Classifications
HY-164018A Related Classifications
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