PMEG-DP disodium
PMEG-DP disodium is a potent DNA polymerase inhibitor (IC50=2.5 μM), especially for DNA polymerase α and δ. PMEG-DP disodium acts as an active metabolite of G-9191, which effectively inhibits the growth of papillomavirus (HPV) -infected cell lines. PMEG-DP disodium can be used in the study of HPV-related diseases.
For research use only. We do not sell to patients.
- Formula: C8H12N5Na2O11P3
- Molecular Weight:493.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
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DNA Polymerase |
Chemical Information
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Molecular Weight 493.11
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Formula C8H12N5Na2O11P3
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SMILES
O=C1N=C(NC2=C1N=CN2CCOCP(O)(OP(O)(OP(O[Na])(O[Na])=O)=O)=O)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wolfgang G H I, et al. GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl) guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions[J]. Antimicrobial agents and chemotherapy, 2009, 53(7): 2777-2784. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PMEG-DP disodium Related Classifications
HY-164018A Related Classifications
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