PqsR/LasR-IN-3
Based on 1 Customer Validation
PqsR/LasR-IN-3 (Compound 7a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-3 also inhibits hERG with the IC50 of 109.01 µM.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 2581109-51-3
- Formula: C14H17NO5S
- Molecular Weight:311.35
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Antibiotic Isoforms
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Biological Activity
PqsR, LasR[1]
Chemical Information
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CAS No. 2581109-51-3
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Appearance Solid
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Molecular Weight 311.35
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Formula C14H17NO5S
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Color White to off-white
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SMILES
O=C(NC1CCOC1=O)CCCS(=O)(C2=CC=CC=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (321.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2118 mL | 16.0591 mL | 32.1182 mL | 80.2955 mL |
| 5 mM | 0.6424 mL | 3.2118 mL | 6.4236 mL | 16.0591 mL | |
| 10 mM | 0.3212 mL | 1.6059 mL | 3.2118 mL | 8.0295 mL | |
| 15 mM | 0.2141 mL | 1.0706 mL | 2.1412 mL | 5.3530 mL | |
| 20 mM | 0.1606 mL | 0.8030 mL | 1.6059 mL | 4.0148 mL | |
| 25 mM | 0.1285 mL | 0.6424 mL | 1.2847 mL | 3.2118 mL | |
| 30 mM | 0.1071 mL | 0.5353 mL | 1.0706 mL | 2.6765 mL | |
| 40 mM | 0.0803 mL | 0.4015 mL | 0.8030 mL | 2.0074 mL | |
| 50 mM | 0.0642 mL | 0.3212 mL | 0.6424 mL | 1.6059 mL | |
| 60 mM | 0.0535 mL | 0.2677 mL | 0.5353 mL | 1.3383 mL | |
| 80 mM | 0.0401 mL | 0.2007 mL | 0.4015 mL | 1.0037 mL | |
| 100 mM | 0.0321 mL | 0.1606 mL | 0.3212 mL | 0.8030 mL |