PROTAC erf3a Degrader-1
Based on 1 Customer Validation
PROTAC erf3a Degrader-1 (Compound C63) is an orally active PROTAC erf3a Degrader. PROTAC erf3a Degrader-1 inhibits cancer cell proliferation (eg: 22Rv1). PROTAC erf3a Degrader-1 can be used for research of prostate cancer, ovarian cancer, liver cancer, cervical cancer, leukemia, breast cancer.
(Pink: eRF3a/GSPT1 Target protein ligand; Blue: Cereblon ligand (HY-41547); Black: linker (HY-163960)).
For research use only. We do not sell to patients.
- Purity: 99.44%
- CAS No.: 3033871-19-8
- Formula: C44H52N6O6
- Molecular Weight:760.92
-
Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All PROTACs Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 3033871-19-8
-
Appearance Solid
-
Molecular Weight 760.92
-
Formula C44H52N6O6
-
Color Light yellow to yellow
-
SMILES
O=C(N1[C@@H]2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H](CCC4)C[C@@H]4NC5=CC(NC([C@H]6CC[C@]([C@@]7([H])[C@@](CC8)([H])[C@@]9([C@@](NC(C=C9)=O)([H])CC7)C)([H])[C@]86C)=O)=CC=C5)=C3C1=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 60 mg/mL (78.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3142 mL | 6.5710 mL | 13.1420 mL | 32.8550 mL |
| 5 mM | 0.2628 mL | 1.3142 mL | 2.6284 mL | 6.5710 mL | |
| 10 mM | 0.1314 mL | 0.6571 mL | 1.3142 mL | 3.2855 mL | |
| 15 mM | 0.0876 mL | 0.4381 mL | 0.8761 mL | 2.1903 mL | |
| 20 mM | 0.0657 mL | 0.3285 mL | 0.6571 mL | 1.6427 mL | |
| 25 mM | 0.0526 mL | 0.2628 mL | 0.5257 mL | 1.3142 mL | |
| 30 mM | 0.0438 mL | 0.2190 mL | 0.4381 mL | 1.0952 mL | |
| 40 mM | 0.0329 mL | 0.1643 mL | 0.3285 mL | 0.8214 mL | |
| 50 mM | 0.0263 mL | 0.1314 mL | 0.2628 mL | 0.6571 mL | |
| 60 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5476 mL |
PROTAC erf3a Degrader-1 Related Classifications
HY-163938 Related Classifications
Powered by Bioz