PROTAC SMARCA2 degrader-34
PROTAC SMARCA2 degrader-34 (compound 52) is a selective SMARCA2 PROTAC degrader (DC50 in HeLa cell: < 0.1 μM for SMARCA2, > 1 μM for SMARCA4). PROTAC SMARCA2 degrader-34 can be used for study of cancer. (Pink: SMARCA2 ligand (HY-178414) ; Blue: E3 ligand (HY-168055) ; Black: linker).
For research use only. We do not sell to patients.
- Formula: C42H45F3N10O4
- Molecular Weight:810.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 810.87
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Formula C42H45F3N10O4
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SMILES
FC([C@]12N(C[C@H](N3C4=C(CN(CC5CCN(C6=CC=C(CN([C@@H]7C(NC(CC7)=O)=O)C8=O)C8=C6)CC5)C(C)C4)C=N3)C2)C9=CC(C%10=C(C(F)=CC=C%10)O)=NN=C9NC1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)