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Cat. No.: HY-14178A

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(R)-VX-11e

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Based on 1 Customer Validation

(R)-VX-11e (Compound 1) is an ERK2 inhibitor.

For research use only. We do not sell to patients.

Purity: 98.73%
CAS No.: 1680187-43-2
Formula: C₂₄H₂₀Cl₂FN₅O₂
Molecular Weight:500.35

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

(R)-VX-11e Chemical Structure

CAS No.: 1680187-43-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

(R)-VX-11e (Compound 1) is an ERK2 inhibitor^[1].

All ERK Isoforms :

Chemical Information

CAS No. 1680187-43-2
Appearance Solid
Molecular Weight 500.35
Formula C₂₄H₂₀Cl₂FN₅O₂
Color White to off-white
SMILES

O=C(C1=CC(C2=NC(NC3=C(Cl)C=C(F)C=C3)=NC=C2C)=CN1)N[C@@H](CO)C4=CC=CC(Cl)=C4
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : < 1 mg/mL (insoluble or slightly soluble)

View the Complete Stock Solution Preparation Table

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vanderpool D, et al. Residence time and kinetic efficiency analysis of extracellular signal-regulated kinase 2 inhibitors. Anal Biochem. 2015 Mar 15;473:46-52. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
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Chemical Information
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- In Vitro
Purity & Documentation
References

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(R)-VX-11e

MCE Bioactive Compound Library

All ERK Isoforms