1. Cell Cycle/DNA Damage
  2. RAD51
  3. RAD51-IN-1

RAD51-IN-1 

Cat. No.: HY-122705
Handling Instructions

RAD51-IN-1, a derivative of  B02, is a potent inhibitor of RAD51. RAD51-IN-1 can be used for cancer research.

For research use only. We do not sell to patients.

RAD51-IN-1 Chemical Structure

RAD51-IN-1 Chemical Structure

CAS No. : 2101739-18-6

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Description

RAD51-IN-1, a derivative of  B02, is a potent inhibitor of RAD51. RAD51-IN-1 can be used for cancer research[1].

In Vitro

RAD51 is a vital component of the homologous recombination DNA repair pathway and is overexpressed in drug-resistant cancers, including aggressive triple-negative breast cancer (TNBC)[1].
RAD51-IN-1 (10 μM) decreases the ratio of RAD51 positive cells/cH2AX positive cells in MDA-MB-231 cell exposure to 6 Gy irradiation[1].
RAD51-IN-1 (10 μM) significantly inhibits DNA damage induced RAD51 foci formation with 6 Gy irradiation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

373.83

Formula

C₂₂H₁₆ClN₃O

CAS No.
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RAD51-IN-1
Cat. No.:
HY-122705
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