Ranimustine
Ranimustine (MCNU) is a nitrosourea alkylating agent, can be used for research of chronic myelogenous leukemia and polycythemia vera.
For research use only. We do not sell to patients.
- CAS No.: 58994-96-0
- Formula: C10H18ClN3O7
- Molecular Weight:327.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 58994-96-0
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Molecular Weight 327.72
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Formula C10H18ClN3O7
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SMILES
O[C@H]1[C@@H](OC)O[C@H](CNC(N(CCCl)N=O)=O)[C@@H](O)[C@@H]1O
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Synonyms
MCNU
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kameoka Y, et al. Safety and efficacy of high-dose ranimustine (MCNU) containing regimen followed by autologous stem cell transplantation for diffuse large B-cell lymphoma. Int J Hematol. 2018 Nov;108(5):510-515. [Content Brief]
[2]. Watanabe S, et al. Chemotherapeutic choice of ranimustine or nimustine on the basis of regional polyamine levels in rat brain. Methods Find Exp Clin Pharmacol. 2008 Mar;30(2):115-20. [Content Brief]
[3]. Kitajima K, et al. [Chemotherapy of chronic myelogenous leukemia--VP(M) regimen initiated during its chronic phase, and evaluation of MCNU in the phase of blastic crisis]. Gan To Kagaku Ryoho. 1989 Nov;16(11):3573-9. Japanese. [Content Brief]
[4]. Nagai M, et al. [Therapeutic effect of ranimustine (MCNU) on essential thrombocythemia and polycythemia vera]. Gan To Kagaku Ryoho. 1988 Dec;15(12):3267-70. Japanese. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)