Regorafenib (Standard)
Regorafenib (Standard) is the analytical standard of Regorafenib. This product is intended for research and analytical applications. Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98%
- CAS No.: 755037-03-7
- 화학식: C21H15ClF4N4O3
- 분자량:482.82
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 755037-03-7
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분자량 482.82
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화학식 C21H15ClF4N4O3
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SMILES
O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F
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Synonyms
BAY 73-4506 (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Regorafenib (Standard)
- 755037-03-7
- BAY 73-4506 (Standard)
- Reference Standards
- VEGFR
- Autophagy
- PDGFR
- Raf
- RET
- c-Kit
- FGFR
- Tie
- Vascular endothelial growth factor receptor
- Platelet-derived growth factor receptor
- Raf kinases
- SCFR
- CD117
- Fibroblast growth factor receptor
- Angiopoietin receptor
- Antitumorigenic
- antiangiogenic
- tumor
- HUVECs
- Hep3B cell
- HAoSMCs
- NIH-3T3
- Colo-205
- MDA-MB-231
- 786-O
- Inhibitor
- inhibitor
- inhibit