2. Anti-infection Apoptosis
  3. Antibiotic Apoptosis Bacterial
  4. Resistomycin

Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis.

For research use only. We do not sell to patients.

Resistomycin Chemical Structure

Resistomycin Chemical Structure

CAS No. : 20004-62-0

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Resistomycin Related Antibodies

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Description

Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis[1][2][3][4].

In Vitro

Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation[1].
Resistomycin displays a high affinity for GST-Pellino-1 (KD = 2.58 μM) as indicated by surface plasmon resonance[1].
Resistomycin treatment reduced the expression of SNAIL and SLUG in TNBC cells[1].
Resistomycin induced apoptosis and cycle arrest in human hepatocellular carcinoma cells by activating p38 MAPK pathway in vitro and in vivo[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Resistomycin Related Antibodies
Molecular Weight

376.36

Formula

C22H16O6
CAS No.
SMILES

OC1=C(C(C2=C(O)C=C(C)C(C(O)=C3)=C2C4=C3C(C)(C)C5=O)=O)C4=C5C(O)=C1
Structure Classification
Initial Source

Streptomyces sulphureus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Resistomycin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Resistomycin20004-62-0AntibioticApoptosisBacterialapoptosiscell cycle arrestTNBCSNAILSLUGInhibitorinhibitorinhibit

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