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Cat. No.: HY-N18037

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Retinyl linoleate

Retinyl linoleate is a retinol ester storage form of Vitamin A (Retinoic acid) (HY-14649) that exists in organisms. Retinyl linoleate can be synthesized by microsomes of human keratinocytes treated with Vitamin A.

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CAS No.: 631-89-0
Formule: C₃₈H₆₀O₂
Masse moléculaire:548.88

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Retinyl linoleate Chemical Structure

CAS No.: 631-89-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Endogenous Metabolite :

In Vitro

Lipid Metabolism

Retinyl linoleate (100 nM; 48 h) was synthesized by microsomes from cultured human keratinocytes exposed to Retinoic acid (HY-14649), whereas vehicle control microsomes showed barely detectable levels^[7].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 631-89-0
Masse moléculaire 548.88
Formule C₃₈H₆₀O₂
SMILES

CCCCC/C=C\C/C=C\CCCCCCCC(OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Endogenous metabolite
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shmarakov IO, et al. Retinoids stored locally in the lung are required to attenuate the severity of acute lung injury in male mice. Nature communications. 2023 Feb 15;14(1):851.

[2]. Antoine T. Vitamin A deficiency during the perinatal period and first weeks of life modifies vitamin A and lipid postprandial metabolism in both female and male young rats. Molecular nutrition & food research. 2021 Nov;65(21):2100451.

[3]. Brouwer A. Marked alterations in retinoid homeostasis of Sprague—Dawley rats induced by a single ip dose of 10 μg/kg of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Toxicology. 1989 Oct 16;58(3):267-83.

[4]. Said HM, et al. Intestinal uptake of retinol in suckling rats: characteristics and ontogeny. Pediatric research. 1988 Oct;24(4):481-5.

[5]. Levin MS, et al. Cellular retinol-binding proteins are determinants of retinol uptake and metabolism in stably transfected Caco-2 cells. The Journal of biological chemistry. 1993 Apr 15;268(11):8267-76.

[6]. Sorg O, et al. Retinol and retinyl ester epidermal pools are not identically sensitive to UVB irradiation and anti-oxidant protective effect. Dermatology (Basel, Switzerland). 1999;199(4):302-7.

[7]. Kurlandsky SB, et al. Auto-regulation of retinoic acid biosynthesis through regulation of retinol esterification in human keratinocytes. The Journal of biological chemistry. 1996 Jun 28;271(26):15346-52. [Content Brief]

[8]. El Aoud A, et al. Fatty acid/monoglyceride type and amount modulate fat-soluble vitamin absorption from mixed assemblies in mice. Food research international (Ottawa, Ont.). 2024 Mar;180:114073.

[9]. Wei S, et al. Retinyl ester hydrolysis and retinol efflux from BFC-1β adipocytes. Journal of Biological Chemistry. 1997 May 30;272(22):14159-65.

[10]. Tran C, et al. Topical delivery of retinoids counteracts the UVB-induced epidermal vitamin A depletion in hairless mouse. Photochemistry and photobiology. 2001 Apr;73(4):425-31.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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