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Ro 31-7837

APTO-253 (LOR-253) hydrochloride is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 hydrochloride mediates anticancer activity via induction of Kruppel-like factor 4 (KLF4) tumor suppressor. APTO-253 hydrochloride exhibits antiarthritic activity.

For research use only. We do not sell to patients.

  • CAS No.: 120280-33-3
  • Formula: C17H16N2O2
  • Molecular Weight:280.32
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Ro 31-7837 Chemical Structure
    Ro 31-7837 Chemical Structure
CAS No.: 120280-33-3
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  • Ro 31-7837 Chemical Structure
    Ro 31-7837 Chemical Structure
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  • Ro 31-7837