RORγt agonist 1
RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC50 of 20.8 nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy.
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- CAS No.: 2377378-89-5
- Formule: C24H17F6NO5S
- Masse moléculaire:545.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
EC50: 20.8 nM (RORγt)[1]
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2377378-89-5
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Masse moléculaire 545.45
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Formule C24H17F6NO5S
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SMILES
FC1=CC(OC(F)F)=CC(C2=CC=C(CC(CC(O)=O)N3S(C4=CC(C(F)(F)F)=CC=C4)(=O)=O)C3=C2)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RORγt agonist 1 Related Classifications
HY-126321 Related Classifications
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