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Cat. No.: HY-160021

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RORγt agonist 4

RORγt agonist 4 (compound 14) is a potent and selective agonist of RORγt. RORγt agonist 4 significantly enhances metabolic stability. RORγt agonist 4 improves the situation of tumor models of mouse B16F10 melanoma and LLC lung adenocarcinoma.

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CAS No.: 2241769-59-3
Formule: C₂₆H₂₄Cl₂N₂O₄S
Masse moléculaire:531.45

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

RORγt agonist 4 Chemical Structure

CAS No.: 2241769-59-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

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Chemical Information

CAS No. 2241769-59-3
Masse moléculaire 531.45
Formule C₂₆H₂₄Cl₂N₂O₄S
SMILES

N#CC1=C(OC(C)C)C=CC(C2=C(C=C(NC(CC3=CC=C(S(=O)(CC)=O)C=C3)=O)C=C2Cl)Cl)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lu L, et al. Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy. J Med Chem. 2023 Nov 20. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RORγt agonist 4

Voir tous les produits spécifiques à Isoform ROR

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RORγt agonist 4 Related Classifications

HY-160021 Related Classifications

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