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Cat. No.: HY-173056

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Ruthenoleuton

Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC₅₀ of 3.49 μM and a K_i of 0.80 μM. Ruthenoleuton has antioxidant activity and can be used in the research of inflammatory diseases.

For research use only. We do not sell to patients.

Formula: C₁₃H₁₆N₂O₂Ru
Molecular Weight:333.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Ruthenoleuton Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

5-LOX

3.49 μM (IC₅₀)

5-LOX

0.80 μM (Ki)

All Lipoxygenase Isoforms :

Chemical Information

Molecular Weight 333.35
Formula C₁₃H₁₆N₂O₂Ru
SMILES

[][Ru][].CC(c1cccc1)N(O)C(N)=O.c2cccc2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Navarrete E, et al. Development of Ferrocenyl and Ruthenocenyl Zileuton Analogs with Enhanced Bioactivity toward Human 5-Lipoxygenase: Innovation in Drugs for Inflammatory Diseases. Inorg Chem. 2025 Feb 24;64(7):3495-3505. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols
Purity & Documentation
References

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Ruthenoleuton

All Lipoxygenase Isoforms

Biological Activity

Description

IC50 & Target

Chemical Information

Protocols

Purity & Documentation

References

Calculators

Help & FAQs

Ruthenoleuton Related Classifications

HY-173056 Related Classifications

Bioz

Keywords

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IC₅₀ & Target