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Cat. No.: HY-W039443

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(S)-4-Thiazolidinecarboxylic acid

Name: (S)-4-Thiazolidinecarboxylic acid
Brand: MedChemExpress
SKU: HY-W039443
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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(S)-4-Thiazolidinecarboxylic acid (L-4-thioproline) is a glutamate 5-kinase inhibitor with an IC₅₀ of 1.8 mM against LdG5K. (S)-4-Thiazolidinecarboxylic acid can be used in the research of leishmaniasis and Escherichia coli infections.

For research use only. We do not sell to patients.

CAS No.: 45521-09-3
Formula: C₄H₇NO₂S
Molecular Weight:133.17

Storage:

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

(S)-4-Thiazolidinecarboxylic acid Chemical Structure

CAS No.: 45521-09-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
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Biological Activity

Description

IC₅₀ & Target

^[1]

Leishmania

All Parasite Isoforms :

In Vitro

(S)-4-Thiazolidinecarboxylic acid (1 mM) inhibits recombinant Leishmania donovani glutamate 5-kinase (LdG5K) with an IC₅₀ value of 1.8 mM^[1].
(S)-4-Thiazolidinecarboxylic acid exhibits an IC₅₀ of 1 mM against Escherichia coli G5K^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 45521-09-3
Appearance Solid
Molecular Weight 133.17
Formula C₄H₇NO₂S
Color Off-white to light yellow
SMILES

C(O)(=O)[C@H]1CSCN1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sienkiewicz N, et al. Characterisation of a putative glutamate 5-kinase from Leishmania donovani. FEBS J. 2018;285(14):2662-2678. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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