2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. (S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM.

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(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate Chemische Struktur

CAS. Nr. : 2414393-48-7

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Other Forms of (S)-Benzyl 2-cyclopropyl-2-hydroxyacetate:

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate Related Antibodies

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Beschreibung

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2].

Molekulargewicht

206.24

Formel

C12H14O3
CAS. Nr.
Appearance

Liquid (Density: 1.234±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(OCC1=CC=CC=C1)[C@H](C2CC2)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate2414393-48-7TopoisomeraseInhibitorinhibitorinhibit

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