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Cat. No.: HY-10399B

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(S)-Ladostigil

(Synonyms: TV-3279)

(S)-Ladostigil (TV-3279), the S-enantiomer of TV 3326 (HY-10399), is a ChE inhibitor with poor MAO-B inhibitory activity. (S)-Ladostigil has neuroprotective effect

For research use only. We do not sell to patients.

CAS No.: 209394-29-6
Formula: C₁₆H₂₀N₂O₂
Molecular Weight:272.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

(S)-Ladostigil Chemical Structure

CAS No.: 209394-29-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

(S)-Ladostigil (TV-3279), the S-enantiomer of TV 3326 (HY-10399), is a ChE inhibitor with poor MAO-B inhibitory activity. (S)-Ladostigil has neuroprotective effect^[1]

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 209394-29-6
Molecular Weight 272.34
Formula C₁₆H₂₀N₂O₂
SMILES

C#CCN[C@@H]1C2=CC(OC(N(C)CC)=O)=CC=C2CC1
Synonyms

TV-3279
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Uddin MS, et al. TV 3326 for Alzheimer's dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer's-like neuropathology. J Pharm Pharmacol. 2020 Aug;72(8):1001-1012. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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(S)-Ladostigil

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S)-Ladostigil Related Classifications

HY-10399B Related Classifications