1. Metabolic Enzyme/Protease Autophagy
  2. Dipeptidyl Peptidase Autophagy
  3. (S)-Sitagliptin phosphate

(S)-Sitagliptin phosphate  (Synonyms: (S)-MK-0431 phosphate)

Cat. No.: HY-13749C
Handling Instructions

(S)-Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts.

For research use only. We do not sell to patients.

(S)-Sitagliptin phosphate Chemical Structure

(S)-Sitagliptin phosphate Chemical Structure

CAS No. : 823817-58-9

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Description

(S)-Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1].

IC50 & Target

DPP-4

 

Molecular Weight

505.31

Formula

C16H18F6N5O5P

CAS No.
SMILES

O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O)(O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(S)-Sitagliptin phosphate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(S)-Sitagliptin phosphate
Cat. No.:
HY-13749C
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