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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
62 Results for "
PCA
" in MedChemExpress (MCE) Product Catalog:
Products (62)
62 Results for "PCA" in MCE Product Catalog:
17
17 Publications Verification
Synonyms: Orin1001
MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells with an IC50 of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .
3
3 Cited Publications
Synonyms: PSMA I&T; PNT-2002
Zadavotide guraxetan (PSMA I&T; PNT-2002) is an effective inhibitor of prostate-specific membrane antigen (PSMA). Zadavotide guraxetan can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa) .
2
2 Cited Publications
Cat. No.: HY-N7043
CAS No.: 142796-21-2
1
1 Cited Publications
Cat. No.: HY-P0021A
CAS No.: 108963-70-8
Synonyms: Spectrozyme PCA; Chromozym PCA diacetate
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-N12127
CAS No.: 899430-01-4
Target:
1
1 Cited Publications
Cat. No.: HY-P700709
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ENPP1; Nucleotide Diphosphatase; Prev. PDNP1; NPPase; Prev. M6S1; Membrane Component, Chromosome 6, Surface Marker 1; Prev. NPPS; Membrane Component Chromosome 6 Surface Marker 1; PC-1; Plasma-Cell Membrane Glycoprotein 1; PCA1; Alkaline Phosphodiesterase
Species:
Mouse
Source:
HEK293
Category:
Infection Alkaloids Microorganisms Other Alkaloids Marine natural products Disease Research Fields
Target:
Cat. No.: HY-W1048558A
Synonyms: mPEG2000-COOH
Category:
Infection Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Other Families Extract Disease Research Fields
Target:
Cat. No.: HY-P10816
CAS No.: 1426656-94-1
Synonyms: Ac-(DLeu)LLLRVK-Amba
Cat. No.: HY-137557
CAS No.: 1565797-16-1
Synonyms: APN1607; PM-PBB3
Target:
Research Areas:
Florzolotau (APN1607) is a positron emission tomography (PET) ligand that can be used for the detection of Alzheimer's disease (AD) and other tau proteinopathies. Its binding sites are located in the β-sheet of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein, as well as in the C-shaped cavity of SFs. In addition, APN-1607 binds to intraneuronal inclusions in Alzheimer's disease (AD), primary age-related tauopathy (PART) and posterior cortical atrophy (PCA). Florzolotau shows promise for PET imaging studies of neurological disorders, particularly tau proteinopathies .
Cat. No.: HY-129503
CAS No.: 40522-46-1
Category:
Target:
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) cells .
Target:
Research Areas:
VPC-13566, a BF3-specific small molecule, is an androgen receptor (AR) inhibitor. VPC-13566 is effective in inhibiting AR transcriptional activity in vitro as well as the growth of AR-dependent PCa cell lines. VPC-13566 can be used as a chemical probe to help identify unknown AR partners.VPC-13566 can be used for the research of cancer.
Cat. No.: HY-P991342
Synonyms: PCA062 antibody
Cat. No.: HY-RS04997
Target:
Research Areas:
FLVCR1 Human Pre-designed siRNA Set A contains three designed siRNAs for FLVCR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-175243
CAS No.: 2734853-87-1
Target:
Research Areas:
ADAR1-IN-1 is a potent ADAR1 inhibitor. ADAR1-IN-1 significantly suppressed DU-145 cell proliferation (IC50 = 1.11 μM), clonogenicity, migration, and invasion, arrests cell cycle, and induces apoptosis. ADAR1-IN-1 safely and effectively inhibits tumor growth. ADAR1-IN-1 can be used for the study of prostate cancer (PCa) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
