Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
PAK2
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "PAK2" in MCE Product Catalog:
10
7
5
1
1 Cited Publications
NVS-PAK1-C is a potent, ATP-competitive and specific allosteric PAK1 inhibitor probe with IC50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC50=270 nM) and phosphorylated PAK2 (IC50=720 nM) .
AZ13705339 is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers .
Target:
Research Areas:
MRIA9, a chemical probe, is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively .
Cat. No.: HY-RS09987
Target:
Research Areas:
PAK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PAK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-171034
CAS No.: 1604678-82-1
Target:
Research Areas:
PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM). PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFα. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice .
Cat. No.: HY-RS09989
Target:
Research Areas:
PAK2 Rat Pre-designed siRNA Set A contains three designed siRNAs for PAK2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09988
Target:
Research Areas:
Pak2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pak2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-120940A
Purity: 99.77%
AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers .
Cat. No.: HY-146786
CAS No.: 2415295-37-1
ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer .
Cat. No.: HY-P702649
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PKN2; Cardiolipin-Activated Protein Kinase PAK2; Prev. PRKCL2; Protein-Kinase C-Related Kinase 2; PRK2; PKN Gamma; Protein Kinase C-Like 2; PKN2 Protein; PAK-2; PRO2042; STK7; PAK2; Protein Kinase N2; Serine/Threonine-Protein Kinase N2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702745
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK2; P21 (CDKN1A)-Activated Kinase 2; P21 (RAC1) Activated Kinase 2; P21-Activated Kinase 2; PAK65; Gamma-PAK; P21 Protein (Cdc42/Rac)-Activated Kinase 2; PAK-2; S6/H4 Kinase; P58; PAKgamma; Non-Specific Serine/Threonine Protein Kinase; Serine/Threonine-
Species:
Human
Source:
Sf9 insect cells
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
