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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
287 Results for "
Crumbs3 transcript
" in MedChemExpress (MCE) Product Catalog:
Products (287)
287 Results for "Crumbs3 transcript" in MCE Product Catalog:
Cat. No.: HY-119264
CAS No.: 903499-49-0
Domaines de recherche:
PRLX-93936 is a molecular Glues that binds to and reprograms the TRIM21 ubiquitin ligase to degrade nuclear pore complexes. PRLX-93936 binds to TRIM21, forms a ternary complex with TRIM21 and NUP98, and mediates the ubiquitination and proteasomal degradation of NUP98 and other nuclear pore complex proteins. PRLX-93936 induces the loss of short-lived cytoplasmic mRNA transcripts, triggers cancer cell apoptosis (Apoptosis), and inhibits the activated Ras pathway. PRLX-93936 inhibits HIF-1 under hypoxic conditions (IC50 = 0.09 μM in cell-based reporter gene assay). PRLX-93936 suppresses tumor growth in mouse models and improves survival rates in mouse models of multiple myeloma. PRLX-93936 is applicable to research related to pancreatic cancer and multiple myeloma [3].
Domaines de recherche:
PRLX-93936 dihydrochloride is a molecular Glues that binds to and reprograms the TRIM21 ubiquitin ligase to degrade nuclear pore complexes. PRLX-93936 dihydrochloride binds to TRIM21, forms a ternary complex with TRIM21 and NUP98, and mediates the ubiquitination and proteasomal degradation of NUP98 and other nuclear pore complex proteins. PRLX-93936 dihydrochloride induces the loss of short-lived cytoplasmic mRNA transcripts, triggers cancer cell apoptosis (Apoptosis), and inhibits the activated Ras pathway. PRLX-93936 dihydrochloride inhibits HIF-1 under hypoxic conditions (IC50 = 0.09 μM in cell-based reporter gene assay). PRLX-93936 dihydrochloride suppresses tumor growth in mouse models and improves survival rates in mouse models of multiple myeloma. PRLX-93936 dihydrochloride is applicable to research related to pancreatic cancer and multiple myeloma [3].
Cat. No.: HY-145973
CAS No.: 2089461-55-0
Synonyms: m7(3'OMeG)(5')ppp(5')(2'OMeA)pG
Domaines de recherche:
3’OMe-m7GpppAmpG (m7(3'OMeG)(5')ppp(5')(2'OMeA)pG) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3’OMe-m7GpppAmpG effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3’OMe-m7GpppAmpG is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research [3] .
Cat. No.: HY-P99899
CAS No.: 2052591-32-7
Synonyms: PR-1498487
Target:
Domaines de recherche:
Cat. No.: HY-W683756
CAS No.: 16625-69-7
Target:
Telomerase Gap Junction Protein P2X Receptor Calcium Channel Reactive Oxygen Species (ROS) NF-κB SGK TNF Receptor
Domaines de recherche:
Boldine hydrochloride is an aporphine alkaloid telomerase (telomerase) inhibitor (IC50 of 0.17 μM for TERT) and a pannexin/connexin hemichannel blocker, with oral activity and blood-brain barrier permeability. Boldine hydrochloride inhibits telomerase activity through direct interaction with the telomerase ribonucleoprotein and non-competitive binding near the TERT active site, and downregulates hTERT mRNA while shifting alternative splicing toward non-functional transcripts. Boldine hydrochloride blocks Panx1, Cx43, Cx26, and Cx30 hemichannels as well as P2X7 receptor-mediated calcium influx. Boldine hydrochloride exhibits antioxidant, anti-inflammatory, antiproliferative, and cytotoxic activities by scavenging ROS, inhibiting NFκB, dephosphorylating SGK1, and reducing TNF-alpha levels. Boldine hydrochloride can be used in research on breast cancer, Alzheimer's disease, glioblastoma, diabetes, and spinal cord injury [3] .
Cat. No.: HY-145973A
Pureté: ≥99.0%
Synonyms: m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100 mM)
Cat. No.: HY-P81501
Synonyms: KIR2DL3 ; CD158B2, KIRCL23, NKAT2; CD158b2; Killer cell immunoglobulin-like receptor 2DL3 ; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; NKAT2a; NKAT2b; Natural killer-associated transcript 2 (NKAT-2); p58 natural killer cell receptor clone CL-6 (p58 NK receptor CL-6); p58.2 MHC class-I-specific NK receptor
Cat. No.: HY-P72087A
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AQP4; HAQP4; Aquaporin 4; WCH4; MIWC; Aquaporin Type4 transcript Variant C; Mercurial-Insensitive Water Channel; Alternative Protein AQP4; Aquaporin-4; Aquaporin Type4; AQP-4; MLC4
Species:
Human
Source:
E. coli
Cat. No.: HY-P72087
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AQP4; HAQP4; Aquaporin 4; WCH4; MIWC; Aquaporin Type4 transcript Variant C; Mercurial-Insensitive Water Channel; Alternative Protein AQP4; Aquaporin-4; Aquaporin Type4; AQP-4; MLC4
Species:
Human
Source:
E. coli
Cat. No.: HY-P702216
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AQP4; HAQP4; Aquaporin 4; WCH4; MIWC; Aquaporin Type4 transcript Variant C; Mercurial-Insensitive Water Channel; Alternative Protein AQP4; Aquaporin-4; Aquaporin Type4; AQP-4; MLC4
Species:
Mouse
Source:
E. coli Cell-free
Cat. No.: HY-P81501A
Synonyms: KIR2DL3 ; CD158B2, KIRCL23, NKAT2; CD158b2; Killer cell immunoglobulin-like receptor 2DL3 ; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; NKAT2a; NKAT2b; Natural killer-associated transcript 2 (NKAT-2); p58 natural killer cell receptor clone CL-6 (p58 NK receptor CL-6); p58.2 MHC class-I-specific NK receptor
Cat. No.: HY-P72075
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; Interferon Gamma Responsive transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P73708
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GOPC; PDZ Protein Interacting Specifically With TC10; Golgi Associated PDZ And Coiled-Coil Motif Containing; CFTR-Associated Ligand; PIST; Fused In Glioblastoma; FIG; Golgi-Associated PDZ And Coiled-Coil Motif Containing Protein transcript Variant 4; CAL
Species:
Human
Source:
E. coli
Cat. No.: HY-P7488A
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; Interferon Gamma Responsive transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:
Human
Source:
E. coli
Cat. No.: HY-P700529
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; Interferon Gamma Responsive transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:
Bovine
Source:
E. coli
Cat. No.: HY-P78840
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB3; Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM And ITIM Domains), Member 3; Leukocyte Immunoglobulin Like Receptor B3; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3; LIR-3; CD85 Antigen-Like Family Member A; ILT5; Immunoglobulin-Like transcript 5; LIR3; Monocyte Inhibitory Receptor HL9; CD85a; Leucocyte Ig-Like Receptor B3; PIR-B; ILT-5; PIRB; Leukocyte Immunoglobulin-Like Receptor 3; HL9; CD85a Antigen
Species:
Human
Source:
HEK293
Cat. No.: HY-P86921
Synonyms: AIF 1 antibody; AIF-1 antibody; Aif1 antibody; AIF1 protein antibody; AIF1_HUMAN antibody; Allograft inflammatory factor 1 antibody; Allograft inflammatory factor 1 splice variant G antibody; allograft inflammatory factor-1 splice variant Hara-1 antibody; balloon angioplasty responsive transcription antibody; BART 1 antibody; AIF 1 antibody; AIF-1 antibody; Aif1 antibody; AIF1 protein antibody; AIF1_HUMAN antibody; Allograft inflammatory factor 1 antibody; Allograft inflammatory factor 1 splice variant G antibody; allograft inflammatory factor-1 splice variant Hara-1 antibody; balloon angioplasty responsive transcription antibody; BART 1 antibody; G1 antibody; G1 putative splice variant of allograft inflamatory factor 1 antibody; IBA 1 antibody; IBA1 antibody; interferon gamma responsive transcript antibody; Interferon responsive transcript 1 antibody; interferon responsive transcript factor 1 antibody; Ionized calcium binding adapter molecule 1 antibody; Ionized calcium-binding adapter molecule 1 antibody; ionized calcium-binding adapter molecule antibody; IRT 1 antibody; IRT1 antibody; Microglia response factor antibody; MRF1 antibody; Protein g1 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
