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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
382 Results for "
diphosphate
" in MedChemExpress (MCE) Product Catalog:
Products (382)
382 Results for "diphosphate" in MCE Product Catalog:
Cat. No.: HY-E71156
Target:
Research Areas:
1,4-Dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) catalyses a step in the synthesis of menaquinone, in which the prenyl chain synthesized by polyprenyl diphosphate synthase is transferred to 1,4-Dihydroxy-2-naphthoate (DHNA) . 1,4-Dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) is an inner membrane protein, with the C-terminus located in the periplasm. 1,4-Dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) is highly specific for DHNA but not for a specific length of the prenyl chain.
Cat. No.: HY-P79310
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPA1; Pyrophosphatase (Inorganic) 1; Prev. PP; Epididymis Secretory Sperm Binding Protein Li 66p; Pyrophosphate Phospho-Hydrolase; diphosphate Phosphohydrolase; IOPPP; Pyrophosphatase (Inorganic); Inorganic Pyrophosphatase; Inorganic Diphosphatase; SID6-8
Species:
Others
Source:
E. coli
Cat. No.: HY-P81289A
Synonyms: NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1
Cat. No.: HY-P85299
Synonyms: NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1
Cat. No.: HY-185150
CAS No.: 114088-58-3
Synonyms: 9-(2-Phosphonylmethoxy)ethylguanine
Target:
Research Areas:
PMEG is a nuclear DNA polymerases α, δ, and ε inhibitor that causes DNA chain termination, inhibits DNA synthesis, induces cytotoxicity in dividing cells. PMEG is an acyclic nucleotide phosphonate that forms an active phosphorylated metabolite, PMEG diphosphate, within cells. PMEG has activity against leukemia and melanoma in rodent models. PMEG has poor cell permeability; its prodrug is Rabacfosadine (GS-9219) (HY-13640). PMEG shows antiviral activity against against various DNA virus infections including murine cytomegalovirus (MCMV) and human cytomegalovirus (HCMV). PMEG can be used for the research of non-hodgkin's lymphoma [1][2].
Cat. No.: HY-P81289AA
Synonyms: NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1
Cat. No.: HY-15592S4
Synonyms: GSK-1265744-d6; S/GSK1265744-d6
Cat. No.: HY-E70052
CAS No.: 128449-51-4
Synonyms: GGTA1
Target:
Research Areas:
alpha-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) catalyzes the generation of the α-gal glycan via the transfer of a galactose (Gal) in α1-3 linkage, from a uridyl-diphosphate (UDP) donor onto the N-acetyllactosamine (Galβ1,4GlcNAc-R) of glycoproteins. alpha-1,3-Galactosyltransferase (a1,3GalT) is responsible for the synthesis of the α-galactose (α-Gal) epitope found in most mammalian species .
Cat. No.: HY-156584
CAS No.: 1626364-18-8
Target:
Research Areas:
ODE-Bn-PMEG is an antiviral compound with strong inhibitory activity against HPV-11, -16, and -18. ODE-Bn-PMEG effectively reduced transient amplification of viral DNA in transfected cells at concentrations well below its cytotoxic levels. ODE-Bn-PMEG showed increased uptake in human foreskin fibroblasts and was able to be efficiently converted to the active antiviral metabolite PMEG diphosphate in vitro. The P-chiral enantiomer of ODE-Bn-PMEG showed comparable antiviral activity, indicating its potential application against multiple HPV types. ODE-Bn-PMEG is a promising candidate for local inhibition of HPV-16, HPV-18, and other high-risk types .
Cat. No.: HY-P71567
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: OGDH; Alpha-Ketoglutarate Dehydrogenase; Oxoglutarate Dehydrogenase; Alpha-KGDH-E1; OGDC-E1; OGDH-E1; Thiamine diphosphate (ThDP)-Dependent 2-Oxoglutarate Dehydrogenase; HsOGDH; 2-Oxoglutarate Dehydrogenase Complex Component E1; E1o; 2-Oxoglutarate Dehydr
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P77273
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CMPK1; CK; Prev. CMPK; Cytidylate Kinase; UMP-CMP Kinase; UMP/CMPK; UMP/CMP Kinase; UMPK; Uridine Monophosphate/Cytidine Monophosphate Kinase; CMK; Nucleoside-diphosphate Kinase; UMK; Deoxycytidylate Kinase; Cytidine Monophosphate Kinase; DCMP Kinase; Uri
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P77273A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CMPK1; CK; Prev. CMPK; Cytidylate Kinase; UMP-CMP Kinase; UMP/CMPK; UMP/CMP Kinase; UMPK; Uridine Monophosphate/Cytidine Monophosphate Kinase; CMK; Nucleoside-diphosphate Kinase; UMK; Deoxycytidylate Kinase; Cytidine Monophosphate Kinase; DCMP Kinase; Uri
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-167632
CAS No.: 31272-50-1
Synonyms: (3R,3′S)-Zeaxanthin
Target:
Reactive Oxygen Species (ROS) Cytochrome P450 COX NO Synthase TNF Receptor UGT Glutathione S-transferase
Research Areas:
meso-Zeaxanthin ((3R,3′S)-Zeaxanthin) is an orally active xanthophyll carotenoid. meso-Zeaxanthin inhibits CYP1A1, CYP1A2, CYP2B1/2, COX-2, TNF-α and iNOS, and enhances the activities of Uridine diphosphate glucuronosyltransferase and Glutathione-S-transferase. meso-Zeaxanthin quenches oxygen free radicals. meso-Zeaxanthin filters short-wavelength blue light, alleviates oxidative damage and visual abnormalities. meso-Zeaxanthin reduces tumor incidence, prolongs tumor latency and survival rate of tumor-bearing mice, and inhibits paw edema. meso-Zeaxanthin can be used in research related to sarcoma and age-related macular degeneration .
Cat. No.: HY-177787A
Target:
Research Areas:
2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .
Cat. No.: HY-P74740
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NUDT1; Methylated Purine Nucleoside Triphosphate Hydrolase; Prev. MTH1; 8-Oxo-7,8-Dihydrodeoxyguanosine Triphosphatase; 7,8-Dihydro-8-Oxoguanine Triphosphatase; Nucleoside diphosphate-Linked Moiety X Motif 1; Nudix Motif 1; 8-Oxo-7,8-Dihydroguanosine Trip
Species:
Human
Source:
E. coli
Cat. No.: HY-P76534
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RRM2B; P53-Inducible Ribonucleotide Reductase Small Subunit 2 Short Form Beta; Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B; P53-Inducible Ribonucleotide Reductase Small Subunit 2 Homolog; P53R2; Ribonucleoside-diphosphate Reductase; P53
Species:
Human
Source:
E. coli
Cat. No.: HY-112747
CAS No.: 97281-51-1
Synonyms: LPI; PE (soy)
Target:
Research Areas:
Soy PE (LPI) is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E.coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions .
Cat. No.: HY-P71267
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RRM2; FLJ25102; Prev. C2orf48; Chromosome 2 Open Reading Frame 48; Ribonucleoside-diphosphate Reductase Subunit M2; Uncharacterized Protein C2orf48; Ribonucleotide Reductase Small Subunit; RR2M; Ribonucleotide Reductase Small Chain; R2; Ribonucleotide Red
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
