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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
AE
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "AE" in MCE Product Catalog:
Cat. No.: HY-P11446A
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Cat. No.: HY-121727
CAS No.: 874195-61-6
Synonyms: AE 1887196; BCS-BX60309
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Triafamone (AE 1887196) is a paddy field pre-emergence and post-emergence sulfonamide herbicide. Triafamone weeds by
inhibiting the acetolactate synthase (ALS) enzyme, thereby blocking the biosynthesis of branched-chain amino acids .
AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 μM and 0.245 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research .
Cat. No.: HY-165407
CAS No.: 99453-84-6
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Neltenexine is a mucolytic agent and an inhibitor of anion hypersecretion. Neltenexine acts on NKCC1, NBC1 and AE2 transporters located on the basolateral membrane of airway epithelial cells . Neltenexine reduces Cl -/HCO3 - uptake by inhibiting NKCC1 and NBC1, activates AE2 to promote Cl - excretion, reduces β2-adrenergic agonist-induced anion hypersecretion without blocking CFTR channels, and maintains appropriate airway fluid levels . Neltenexine can be used in research related to chronic obstructive pulmonary disease and emphysema .
Cat. No.: HY-50901A
CAS No.: 2309931-05-1
Synonyms: AE 3-208 sodium salt
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ONO-AE3-208 (sodium salt) is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM. ONO-AE3-208 (sodium salt) shows less potently affects EP3, FP, and TP receptors (Ki of 30 nM, 790 nM, and 2400 nM, respectively). ONO-AE3-208 (sodium salt) suppresses cell invasion, migration, and metastasis of prostate cancer .
Cat. No.: HY-U00284
CAS No.: 116308-56-6
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AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease.
Cat. No.: HY-163662
CAS No.: 1011351-65-7
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AE027 is a potent inhibitor against both WT and resistant mutation F348Y AChE with the IC50 values of 10 and 43 μM, respectively .
Cat. No.: HY-134971
CAS No.: 893426-98-7
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AE9C90CB is an M3 muscarinic receptor (mAChR) antagonist and M2 muscarinic receptor ligand (human pKi values of 9.9 and 8.6, respectively). AE9C90CB binds to the M3 receptor and produces an insurmountable antagonism of Carbamoylcholine chloride (HY-B1208)-induced bladder strip contraction, thereby inhibiting the elevation of intravesical pressure and salivation, and exhibits functional selectivity for the bladder relative to the salivary glands. AE9C90CB can be used in the study of overactive bladder .
Cat. No.: HY-N12273
CAS No.: 117230-34-9
Synonyms: Acetyl-soyasaponin A5
Category:
Triterpenes Glycine max (L.) merr Terpenoids Leguminosae Extract Plants Pentacyclic Triterpenoids
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Cat. No.: HY-167103A
CAS No.: 433232-03-2
Synonyms: ONO-AE1-259
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ONO-8815Ly (ONO-AE1-259) is a selective EP2 receptor agonist. ONO-8815Ly inhibits spontaneous uterine contractility .
Cat. No.: HY-14338AR
CAS No.: 467458-02-2
Synonyms: Lu AE58054 hydrochloride (Standard)
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Idalopirdine (hydrochloride) (Standard) is the analytical standard of Idalopirdine (hydrochloride). This product is intended for research and analytical applications. Idalopirdine hydrochloride (Lu AE58054 hydrochloride) is a potent, selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM. Idalopirdine hydrochloride may be used in studies of Alzheimer's disease and schizophrenia, among other related disorders .
Cat. No.: HY-106832A
CAS No.: 133743-71-2
Synonyms: Watanidipine hydrochloride; AE0047
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Vatanidipine (Watanidipine) hydrochloride is an orally active dihydropyridine (DHP)-type calcium channel blocker and a useful antihypertensive agent. Vatanidipine hydrochloride shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings .
Cat. No.: HY-159526
CAS No.: 1246013-02-4
Synonyms: DOTA-AE105
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Cat. No.: HY-106832
CAS No.: 116308-55-5
Synonyms: Watanidipine; AE0047 free base
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Vatanidipine (Watanidipine) is an orally active dihydropyridine (DHP)-type calcium channel blocker and a useful antihypertensive agent. Vatanidipine shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings .
Cat. No.: HY-W042301R
CAS No.: 14293-44-8
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Xipamide (Standard) is the analytical standard of Xipamide. This product is intended for research and analytical applications. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) .
Cat. No.: HY-106699
CAS No.: 87440-45-7
Synonyms: CG 4203 sodium
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Taprostene sodium is a partial agonist at prostanoid prostacyclin (IP) receptors. Taprostene sodium interacts additively with Prostaglandin E2 (PGE2) (HY-101952), ONO-AE1-259 (selective EP2 agonist), and acetylcholine. Taprostene sodium exerts a significant cardioprotection .
Cat. No.: HY-169166
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HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR, R41T HIV-1 PR, respectively. HIV-1 protease-IN-14 shows low cytotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
