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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
355 Results for "
Domain B
" in MedChemExpress (MCE) Product Catalog:
Products (355)
355 Results for "Domain B" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P72815
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ADAM17; Snake Venom-Like Protease; Prev. TACE; ADAM Metallopeptidase Domain 18; CSVP; Uncharacterized Protein ADAM17; Disintegrin And Metalloproteinase Domain-Containing Protein 17; TNF-Alpha Converting Enzyme; TNF-Alpha Convertase; CD156b Antigen; CD156B
Species:
Rat
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72428
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V-Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7-H5; PD-1H; Dies1; GI24; B7H5; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; V-Set Domain-Containing Immunoregulatory Receptor; V-Domain Ig Suppressor Of T Cell Ac
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74395
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VTCN1; V-Set Domain Containing T Cell Activation Inhibitor 1; B7-H4; B7H4; B7h.5; B7S1; B7x; V-Set Domain-Containing T-Cell Activation Inhibitor 1; Immune Costimulatory Protein B7-H4; B7 Superfamily Member 1; B7 Family Member, H4; B7 Homolog 4; FLJ22418;
Species:
Human
Source:
HEK293
1
1 Cited Publications
Target:
Research Areas:
NVS-STG2 is a molecular glue that targets STINGb and activates STING-mediated immune signaling. NVS-STG2 induces higher-order oligomerization of human STING by binding to pockets between adjacent STING dimer transmembrane domains, effectively acting as a molecular glue. NVS-STGI enhances the activity of cGAMP by inducing the formation of more abundant and larger oligomers. NVS-STG2 produces antitumor activity in animal models .
1
1 Cited Publications
Cat. No.: HY-P76079
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SMYD2; Histone Methyltransferase SMYD2; SET And MYND Domain Containing 2; ZMYND14; HSKM-B; Lysine N-Methyltransferase 3C; KMT3C; [Histone H3]-Lysine(4) N-Trimethyltransferase; SET And MYND Domain-Containing Protein 2; Zinc Finger, MYND Domain Containing 1
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P5982
Research Areas:
1
1 Cited Publications
Cat. No.: HY-W017113
CAS No.: 149-30-4
1
1 Cited Publications
Cat. No.: HY-P7864
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P700862
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; Complement Component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P78247
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: C3; Complement Component 3; Complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74177
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein EGFR; Erb-B2 Receptor Tyrosine Kinase 1; Epidermal Growth Factor; Proto-Oncogene C-ErbB-1; EGFR VIII; HER1; NISBD2; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); NNCIS; Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian); PIG61; Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog; MENA; Epidermal Growth Factor Receptor Tyrosine Kinase Domain; Epidermal Growth Factor Receptor; Epidermal Growth Factor Receptor Variant EX12_15del
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P7710
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALM1; Epididymis Secretory Protein Li 72; Prev. CALML2; Calmodulin-3; DD132; CAMIII; PHKD1; CPVT4; CAMI; LQT14; PHKD; CALM3; Calmodulin 1 (Phosphorylase Kinase, Delta); CALM2; Phosphorylase Kinase Subunit Delta 1; CAM2; Phosphorylase Kinase Subunit Delta; CAM3; Prepro-Calmodulin 1; CAMB; Calmodulin-1; CAMC; Calmodulin 3 (Phosphorylase Kinase, Delta), Isoform CRA_b; CAM1; Calmodulin 1 (Phosphorylase Kinase, Delta), Isoform CRA_a; CALM; EF-Hand Calcium-Binding Domain-Containing Protein 11; CaM; CDNA FLJ61744, Highly Similar To Calmodulin; CAM; Phosphorylase Kinase, Delta Subunit; Calmodulin 1; Calmodulin-2
Species:
Human
Source:
E. coli
Cat. No.: HY-164607
CAS No.: 3056857-07-6
Target:
Research Areas:
YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. YL-5092 can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 can be used for the research of cancer, such as acute myeloid leukemia (AML) .
Cat. No.: HY-P99621
CAS No.: 2467411-25-0
Synonyms: NPC-21; EV2038
Cat. No.: HY-P99010A
Target:
Research Areas:
Target:
Research Areas:
M1001 is a weak hypoxia-inducible factor-2α (HIF-2α) agonist. M1001 can bind to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 can be used in chronic kidney disease research .
Cat. No.: HY-P5421
CAS No.: 898221-46-0
Target:
Research Areas:
Cat. No.: HY-P99875
CAS No.: 2252477-42-0
Synonyms: BIVV-001; Altuvoct
Target:
Research Areas:
Cat. No.: HY-161745
CAS No.: 2941386-60-1
Research Areas:
PBA-1105b is an autophagy-targeting chimera (AUTOTAC) that induces p62 self-oligomerization. PBA-1105b binds to the ZZ domain of p62, inducing conformational activation and self-oligomerization for autophagy targeting. PBA-1105b is used in research on neurodegenerative diseases .
Cat. No.: HY-163035
CAS No.: 1206480-93-4
Target:
Research Areas:
EM-163 is a summative BB-Loop analog. EM-163 can alleviate inflammation and prevent death from toxic shock by targeting the TIR domain of MyD88. EM-163 can be used in the study of SEB poisoning (SEB: Staphylococcal enterotoxin B) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
