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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
355 Results for "
Domain B
" in MedChemExpress (MCE) Product Catalog:
Products (355)
355 Results for "Domain B" in MCE Product Catalog:
Cat. No.: HY-115671
Purity: 99.99%
Target:
Research Areas:
KLH45b is an inhibitor of DDHD2 (DDHD domain containing 2) .
Cat. No.: HY-P99487
CAS No.: 869881-54-9
Synonyms: BR 3FC
Target:
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Cat. No.: HY-122735
CAS No.: 690216-38-7
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Inh2-B1 is a Ser/Thr protein kinase (STK1) inhibitor. Inh2-B1 specifically inhibits STK1 activity by directly binding to its ATP-binding catalytic domain. Inh2-B1 down-regulates cell wall hydrolase genes and disrupts the biofilm formation of Methicillin-resistant Staphylococcus aureus (MRSA) clearly .
Cat. No.: HY-P10550
Cat. No.: HY-P991779
Cat. No.: HY-P991680
CAS No.: 3037408-21-9
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Research Areas:
Cat. No.: HY-W012248
CAS No.: 349-58-6
KG-655 is a ligand that specifically binds to the ARNT PAS-B domain. KG-655 binds to the internal cavity of ARNT PAS-B to restrict its variable folded conformation, disrupts the interaction between ARNT PAS-B and the transcriptional coactivator TACC3, and promotes the homodimerization of ARNT PAS-B. KG-655 is widely applicable to cancer-related research .
Cat. No.: HY-177756
CAS No.: 2230406-60-5
BCL6-IN-11 is a potent inhibitor of the BCL6 BTB domain and a partial degrader of BCL6. BCL6-IN-11 inhibits the interaction between the BCL6 BTB domain and BCOR with an IC50 of 6 nM. BCL6-IN-11 can be used for research related to BCL6 degradation in diffuse large B-cell lymphoma (DLBCL) .
Cat. No.: HY-P991092
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IBI-334 is a bispecific B7-H3 and EGFR antibody. IBI-334 has an EGFR arm for signal blockage and is coupled with a fine-tuned B7-H3 arm with optimal affinity and binding domain. IBI-334 shows antibody-mediated cell cytotoxicity (ADCC) effects. IBI-334 has a wide range of applications in many EGFR-driven solid tumors .
Cat. No.: HY-P5330
CAS No.: 505070-10-0
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Cat. No.: HY-170674
Target:
Research Areas:
ND-L11B is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with the DC50 of 1.48 and 0.8 μM, the Dmax is closed to 80 % .
Cat. No.: HY-170674A
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ND-L11B TFA is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with the DC50 of 1.48 and 0.8 μM, the Dmax is closed to 80 % .
Cat. No.: HY-148384A
CAS No.: 2925647-93-2
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UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 μM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF 65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing .
Cat. No.: HY-P5947
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Cat. No.: HY-161732
CAS No.: 2982663-28-3
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GQN-B37-E is a potent selective binder and inhibitor of MCL-1. GQN-B37-E binds to the BH3-domain-binding pocket in MCL-1. GQN-B37-E exhibits binding affinity for MCL-1 at the submicromolar range (Ki = 0.6 μM) without apparent binding to BCL-2 or BCL-XL .
Cat. No.: HY-B0563BS
CAS No.: 1217667-10-1
Cat. No.: HY-P990986
CAS No.: 2922216-49-5
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Cat. No.: HY-P990992
CAS No.: 2922216-50-8
Synonyms: GI-102
Target:
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Cat. No.: HY-P71284
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SEMA4B; Semaphorin-4B; Prev. SEMAC; MGC131831; KIAA1745; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, 4B; SemC; SEMA4B Protein; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Shor
Species:
Human
Source:
HEK293
Cat. No.: HY-P78034
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SEMA4B; Semaphorin-4B; Prev. SEMAC; MGC131831; KIAA1745; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, 4B; SemC; SEMA4B Protein; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Shor
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
