305 Results for "

NF-YB/NF-YC dimer

" in MedChemExpress (MCE) Product Catalog:
Products (305)

305 Results for "NF-YB/NF-YC dimer" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-157214
CAS No.: 3030588-01-0
Purity:  99.76%
Target:  

STING Molecular Glues

Research Areas:  

Cancer

NVS-STG2 is a molecular glue that targets STINGdimer transmembrane domains, effectively acting as a molecular glue. NVS-STGI enhances the activity of cGAMP by inducing the formation of more abundant and larger oligomers. NVS-STG2 produces antitumor activity in animal models .
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1
1 Cited Publications
Cat. No.: HY-P1441A
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Mambalgin 1 TFA is a selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively). Mambalgin 1 TFA binds to closed/inactive channel. Mambalgin 1 TFA is selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Mambalgin 1 TFA increases latency of withdrawal response in mouse tail-flick and paw-flick tests.
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1
1 Cited Publications
Cat. No.: HY-W040129
CAS No.: 7059-24-7
Chromomycin A3 is an inhibitor that selectively binds to GC-rich DNA sequences. Chromomycin A3 targets the DNA minor groove after forming a dimer with Mg 2+. Chromomycin A3 inhibits DNA replication and transcription, blocks the binding of Sp1 transcription factor to target gene promoters, downregulates the expression of anti-apoptotic proteins such as FLIP, Mcl-1, and XIAP, and induces S-phase cycle arrest and caspase-dependent apoptosis in tumor cells. Chromomycin A3 can antagonize oxidative stress induced by glutathione depletion and neuronal apoptosis induced by Camptothecin (HY-15660). Chromomycin A3 can be used in basic research on malignant tumors such as cholangiocarcinoma, and is a potential chemosensitizer and GC-rich region probe .
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Cat. No.: HY-101127
CAS No.: 1222490-34-7
Purity:  98.45%
Synonyms: PBD dimer
Target:  

ADC Payloads

Research Areas:  

Cancer

SGD-1882 is a cytotoxic, DNA minor-groove crosslinking agent pyrrolobenzodiazepine (PBD) dimer, acting as the payload for ADCs.
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Cat. No.: HY-W008260
CAS No.: 12112-67-3
Synonyms: Chloro-1,5-cYClooctadiene iridium(I) dimer
[Ir(cod)Cl]2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W019734
CAS No.: 12354-85-7
Synonyms: PentamethylcYClopentadienylrhodium(III) chloride dimer
[Rh(Cp*)Cl2]2 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W001951
CAS No.: 15956-28-2
Synonyms: Tetrakis(acetato)dirhodium(II); Rhodium(II) acetate dimer
Dirhodium tetraacetate (Tetrakis (acetato) dirhodium (II)) is an anticancer agent. Dirhodium tetraacetate functionally inhibits the activities of DNA polymerase I and RNA polymerase. It also acts as a catalyst and can be used to construct rhodium-based artificial metalloenzymes .
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Cat. No.: HY-W018845
CAS No.: 12354-84-6
Synonyms: PentamethylcYClopentadienyliridium(III) chloride,dimer
[Ir(Cp-)Cl2]2 is used as a precursor for the asymmetric transfer hydrogenation catalyst of ketones. It is a catalyst for greener amine synthesis .
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Cat. No.: HY-148424
CAS No.: 145325-57-1
Purity:  98.03%
Research Areas:  

Cancer

PBD dimer-2 (compound 2c) is a C8-linked pyrrolobenzodiazepine dimer. PBD dimer-2 can span an extra base pair and cross-link the 5′-Pu-GA(T/A)TC-Py sequence. PBD dimer-2 can be used as a payload for antibody–agent conjugates (ADCs), and it can be used for the research of cancer .
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Cat. No.: HY-P99917
CAS No.: 2200269-84-5
Synonyms: F-652; rhIL-22 dimer

Target:  

STAT

Research Areas:  

Infection Inflammation/Immunology

Eflepedocokin alfa is a recombinant fusion protein. Eflepedocokin alfa consists of human IL-22 fused to human IgG2-Fc domain. Eflepedocokin alfa leads to the activation of IL-22/IL-22R-mediated signal transduction pathways as well as STAT3. Eflepedocokin alfa plays a role in immune response and bacterial infection, enhancing intestinal barrier function, intestinal immunity, and tissue repair .
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Cat. No.: HY-D1602
CAS No.: 217075-07-5
Target:  

Fluorescent Dye

Research Areas:  

Others

BODIPY FL-DHPE is a fluorescent lipid probe composed of phosphatidylethanolamine (DHPE) labeled with a BODIPY FL fluorophore, which is used for fluorescent labeling of cell membranes, differentiation between liposome membrane fusion and endocytic pathways, and studies of membrane dynamics. The two C16 alkyl chains of BODIPY FL-DHPE insert into the lipid bilayer of membranes, and its fluorescence exhibits concentration dependence: it exists as monomers and emits green fluorescence at low mole fractions; it forms dimers with a red-shifted emission peak at high mole fractions; this spectral change is independent of enzymes, pH, and membrane potential. When liposomes enter the plasma membrane via membrane fusion, the dye is diluted, leading to attenuation of the dimer peak and enhancement of the monomer peak; when entry occurs via endocytosis, the dye remains in endosomes at high concentration with no change in the dimer peak, allowing differentiation between the two uptake pathways. Ex = 488 nm; monomer Em = 515 nm, dimer Em ≈ 620 nm .
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Cat. No.: HY-153804
CAS No.: 864627-58-7
Purity:  99.68%
Synonyms: NCD
Target:  

Molecular Glues

Research Areas:  

Neurological Disease Cancer

Naphthyridine carbamate dimer (NCD) is a molecular glue. Naphthyridine carbamate dimer induces designed structural changes in target functional DNA, thereby regulating its function. As a molecular glue, naphthyridine carbamate dimer stabilizes non-spontaneously formed GG homologous mismatched double-stranded DNA. Naphthyridine carbamate dimer reduces the formation of toxic RNA foci and regulates CGG repeat instability associated with fragile X syndrome and spinocerebellar ataxia type 31. Naphthyridine carbamate dimer can be used in research related to fragile X syndrome and spinocerebellar ataxia type 31 .
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Cat. No.: HY-D0916
CAS No.: 143413-85-8
Synonyms: YOYO 1; YOYO1
Thiazole orange dimer YOYO 1 (YOYO 1) is a cell-impermeable cyanine dimer with no inherent fluorescence, and its fluorescence intensity increases significantly upon binding to double-stranded DNA (dsDNA) . Thiazole orange dimer YOYO 1 can serve as a nuclear counterstain or a dead cell indicator (Ex/Em = 505/512 nm).
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Cat. No.: HY-Y1109
CAS No.: 52462-29-0
Synonyms: Tetrachlorobis(mu-4-cymene)diruthenium(II)
Research Areas:  

Cancer

Dichloro(p-cymene)ruthenium(II) dimer (Tetrachlorobis(mu-4-cymene)diruthenium(II)) is a ruthenium-based organometallic catalyst precursor, which is widely applied in the field of organic synthesis .
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Cat. No.: HY-W034065
CAS No.: 51863-60-6
3,5-Dihydroxyacetophenone is a drug intermediate that can be used in the synthesis of the active stilbene dimer dehydro-δ-viniferin .
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Cat. No.: HY-W033466
CAS No.: 37366-09-9
Synonyms: Benzeneruthenium(II) chloride dimer
Benzeneruthenium(II) Chloride Dimer (Benzeneruthenium(II) chloride dimer) is a dinuclear complex. Benzeneruthenium(II) Chloride Dimer undergoes a hydrolysis reaction to generate a mixture of mononuclear ruthenium complexes in equilibrium .
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Cat. No.: HY-P3215
CAS No.: 19645-28-4
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
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Cat. No.: HY-P3222
CAS No.: 20054-93-7
Target:  

Inhibitory Antibodies

Research Areas:  

Endocrinology

Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
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Cat. No.: HY-125772
CAS No.: 344327-48-6
Purity:  ≥99.0%
Synonyms: Acetylpodocarpic dimer; APD
Target:  

LXR

Research Areas:  

Cardiovascular Disease

Acetyl podocarpic acid anhydride is a potent, semisynthetic liver X receptor(LXR) agonist derived from extracts of the mayapple. Acetyl podocarpic acid anhydride has the potential to be useful for the prevention and research of atherosclerosis, especially in the context of low HDL levels .
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Cat. No.: HY-W097819
CAS No.: 2092-49-1
Synonyms: Dehydrodivanillin
Divanillin is a dimer composed of two vanillins (HY-N0098) covalently linked .
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