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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
243 Results for "
cytotoxic effect
" in MedChemExpress (MCE) Product Catalog:
Products (243)
243 Results for "cytotoxic effect" in MCE Product Catalog:
1
Category:
Flavonoids Monophenols Flavonones Phenols Leguminosae Extract Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology
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1 Cited Publications
Cat. No.: HY-N0755
CAS No.: 17306-46-6
Category:
Rhus succedanea Flavonoids Anacardiaceae Extract Flavones Plants Disease Research Fields Endocrinology Cancer
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1
1 Cited Publications
BCI-137 is a Argonaute 2 (AGO2) inhibitor. By inhibiting AGO2 function, reducing PTPN6/SHP-1 protein levels and enhancing STAT1 phosphorylation, BCI-137 restores the sensitivity of tumor cells to IFN-γ. BCI-137 effectively enhances the recruitment, activation and cytotoxicity of CD8 + T cells. BCI-137 exerts a synergistic effect with anti-PD-1 antibodies and significantly reduces tumor volume in preclinical mouse models. BCI-137 exhibits favorable safety profiles and does not cause significant weight loss or death in mice. BCI-137 can be used in research related to bladder cancer, colorectal cancer, melanoma and other related fields .
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Cat. No.: HY-P99653
CAS No.: 1929549-92-7
Synonyms: VAY-736
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Cat. No.: HY-P99623
CAS No.: 1664355-28-5
Synonyms: MGD006; S80880
Cat. No.: HY-N6642
CAS No.: 50980-32-0
Cat. No.: HY-P5762
CAS No.: 1415039-79-0
Synonyms: PNX-14
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Synonyms: Naphthafluorescein
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Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.
Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo . Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging .
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Topoisomerase I inhibitor 8 is a potent topoisomerase I inhibitor. Topoisomerase I inhibitor 8 is a hexacyclic analogue of camptothecin, and displays cytotoxic effect against tumor cells .
Cat. No.: HY-N0206
CAS No.: 23643-61-0
Synonyms: Deglucocyclamin; LTS-4; Saxifragifolin B
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Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects. Demoxepam has an inhibitory effect on in vitro [ 3H]tryptophan binding to rat hepatic nuclei .
Cat. No.: HY-P99015
CAS No.: 880486-59-9
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Cat. No.: HY-W020044R
CAS No.: 10191-41-0
Synonyms: DL-α-Tocopherol (Standard)
Cat. No.: HY-13562
CAS No.: 136470-65-0
Synonyms: AQ4N
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Banoxantrone (AQ4N), as a prototype hypoxia selective cytotoxin, can be reduced to AQ4, a potent topoisomerase II inhibitor. Banoxantrone selectively kills hypoxic cells via an iNOS-dependent mechanism. Banoxantrone shows a potent cytotoxicity and hypoxia-selective effect enhanced by radiation .
Cat. No.: HY-N4265
CAS No.: 156009-80-2
Category:
Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae Extract
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4'-Hydroxytamoxifen is a metabolite of Tamoxifen. 4'-Hydroxytamoxifen shows higher affinity for the ER than Tamoxifen. 4'-Hydroxytamoxifen induces a non-apoptotic cytotoxic effect in human endometrial adenocarcinoma cells .
Cat. No.: HY-N8015S
CAS No.: 1219794-66-7
Cat. No.: HY-116885
CAS No.: 220862-05-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
