Thunalbene
Thunalbene is a stilbene derivative isolated from Thunia alba. Thunalbene has a weak inhibitory effect on nitric oxide production and is not cytotoxic.
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- CAS. Nr.: 220862-05-5
- Formel: C15H14O3
- Molecular Weight:242.27
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
Thunalbene (1 or 10 μM) produces a value of 92.92 for NO at a concentration of 1μM and 75.08 for NO at a concentration of 10 μM with no cytotoxicity in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 220862-05-5
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Molecular Weight 242.27
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Formel C15H14O3
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SMILES
OC1=CC(OC)=CC(/C=C/C2=CC=CC(O)=C2)=C1
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Thunalbene Related Classifications
HY-116885 Related Classifications
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