6971 Results for "

factor

" in MedChemExpress (MCE) Product Catalog:
Products (6971)

6971 Results for "factor" in MCE Product Catalog:

62
62 Cited Publications
Art. -Nr.: HY-17567A
CAS. Nr.: 9041-08-1
Synonyms: Sodium heparin; Sodium heparinate
Forschungsgebiete:  

Cardiovascular Disease Cancer

Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions.
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60
60 Cited Publications
Art. -Nr.: HY-P7044
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory factor 2; Interferon, Beta 2; CTL Differ
Species:  
Human
Source:  
E. coli
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58
58 Cited Publications
Art. -Nr.: HY-P70543
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth factor Beta-1;
Species:  
Human
Source:  
HEK293
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57
57 Cited Publications
Art. -Nr.: HY-P7080
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory factor 1; Interleukin 4; B-Cell Stimulatory factor 1; IL-4; B Cell Growth factor 1; Lymphocyte Stimulatory factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:  
Mouse
Source:  
CHO
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57
57 Cited Publications
Art. -Nr.: HY-P9905
CAS. Nr.: 205923-56-4
Synonyms: C225; IMC-C225
Forschungsgebiete:  

Cancer

Cetuximab (C225) is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a Kd of 0.201 nM for EGFR by SPR. Cetuximab has potent antitumor activity .
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54
54 Cited Publications
Art. -Nr.: HY-13251
CAS. Nr.: 697235-38-4
Reinheit:  99.96%
Synonyms: (-)-Silvestrol
Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
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45
45 Cited Publications
Art. -Nr.: HY-P7361
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF2; Molgramostim; Colony Stimulating factor 2; Molgramostin; GMCSF; CSF; Sargramostim; Granulocyte-Macrophage Colony Stimulating factor; GM-CSF; Granulocyte Macrophage-Colony Stimulating factor; Colony Stimulating factor 2 (Granulocyte-Macrophage); Colo
Species:  
Mouse
Source:  
E. coli
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43
43 Cited Publications
Art. -Nr.: HY-108635
CAS. Nr.: 74389-68-7
Reinheit:  99.85%
Synonyms: PAF (C16)
C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by activating the PAFR. C16-PAF is a potent MAPK and MEK/ERK activator. C16-PAF induces increased vascular permeability .
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43
43 Cited Publications
Art. -Nr.: HY-P7004
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF2; BFGF; Prev. FGFB; Basic Fibroblast Growth factor; Fibroblast Growth factor 2 (Basic); Fibroblast Growth factor; Heparin-Binding Growth factor 2; Prostatropin; HBGF-2; FGF2A; FGF-2; FGF; Fibroblast Growth factor 2; Basic Fibroblast Growth factor BFGF
Species:  
Human
Source:  
E. coli
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42
42 Cited Publications
Art. -Nr.: HY-P7090
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; Tumor Necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; Tumor Necrosis factor-Alpha; TNF-Alpha; Tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; Tumor Necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:  
Mouse
Source:  
E. coli
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37
37 Cited Publications
Art. -Nr.: HY-10984
CAS. Nr.: 19171-19-8
Reinheit:  99.88%
Synonyms: CC-4047
Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.
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37
37 Cited Publications
Art. -Nr.: HY-10496
CAS. Nr.: 913822-46-5
Reinheit:  99.24%
Target:  

NF-κB Influenza Virus

Forschungsgebiete:  

Infection Cancer

SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65 . SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins .
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34
34 Cited Publications
Art. -Nr.: HY-15836
CAS. Nr.: 1227158-85-1
Reinheit:  99.40%
Forschungsgebiete:  

Cancer

BAY 87-2243 is a highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
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34
34 Cited Publications
Art. -Nr.: HY-139397
CAS. Nr.: 1357471-57-8
Reinheit:  99.85%
Target:  

MyD88

Forschungsgebiete:  

Cardiovascular Disease

TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway . TJ-M2010-5 can be used for the research of myocardial ischemia/reperfusion injury (MIRI) .
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33
33 Cited Publications
Art. -Nr.: HY-16268
CAS. Nr.: 4727-31-5
Synonyms: KGN
Target:  

TGF-beta/Smad

Forschungsgebiete:  

Inflammation/Immunology

Kartogenin (KGN) is an inducer of chondrogenic tissue formation (EC50: 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research .
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33
33 Cited Publications
Art. -Nr.: HY-16268A
CAS. Nr.: 1401168-39-5
Synonyms: KGN sodium
Target:  

TGF-beta/Smad

Forschungsgebiete:  

Inflammation/Immunology

Kartogenin (KGN) sodium is an inducer of chondrogenic tissue formation (EC50: 100 nM). Kartogenin sodium induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin sodium also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin sodium is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin sodium promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research .
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33
33 Cited Publications
Art. -Nr.: HY-P7063
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory factor 2; Interferon, Beta 2; CTL Differentiation factor; Interleukin BSF-2; Interleukin 6; Interferon Beta-2
Species:  
Mouse
Source:  
E. coli
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32
32 Cited Publications
Art. -Nr.: HY-19356
CAS. Nr.: 84573-16-0
Synonyms: Roc-A
Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia .
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32
32 Cited Publications
Art. -Nr.: HY-P70648
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth factor Beta-1;
Species:  
Rat Mouse
Source:  
HEK293
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31
31 Cited Publications
Art. -Nr.: HY-15494
CAS. Nr.: 477-47-4
Reinheit:  99.85%
Synonyms: AXL1717; Picropodophyllotoxin; PPP
Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
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