128 Results for "

hypotensive

" in MedChemExpress (MCE) Product Catalog:
Products (128)

128 Results for "hypotensive" in MCE Product Catalog:

Cat. No.: HY-152847
CAS No.: 1802655-72-6
Purity:  99.52%
Synonyms: QLS-101
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Foslevcromakalim (QLS-101) is a ATP-sensitive potassium channel opener. Foslevcromakalim is the proagent used for ocular hypotensive effect .
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Cat. No.: HY-W016414
CAS No.: 78-40-0
Triethyl phosphate is a versatile phosphate ester compound. Triethyl phosphate induces rapid and short-acting anesthesia, and exhibits hypotensive, smooth muscle relaxant, and cardiac inhibitory effects. Triethyl phosphate also modulates cholinergic toxicity; its anesthetic effect shows sex- and age-dependency in rodents, and it interacts with SKF 525-A (HY-B1311) to alter the duration of anesthesia .
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Cat. No.: HY-P1831
CAS No.: 150238-87-2
Synonyms: ProAM N20, Human; PAMP-20, human
Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release–inhibitory peptide released from chromaffin cells. Proadrenomedullin (1-20) inhibits catecholamine secretion in PC12 pheochromocytoma cells (IC50 ≈ 350 nM) by suppressing Na +/Ca 2+ influx and blocking desensitization. Proadrenomedullin (1-20), human specifically acts on nicotinic cholinergic receptors in a non competitive manner. Proadrenomedullin (1-20), human can be used for research on conditions such as hypertension .
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Cat. No.: HY-P1106A
Target:  

CFTR

Research Areas:  

Cardiovascular Disease

K41498 TFA is a highly selective CRF 2 receptor antagonist, with a Ki of 0.66 nM for human CRF2α receptor and a Ki of 0.62 nM for human CRF2β receptor. K41498 TFA inhibits cAMP accumulation in cells expressing CRF2. K41498 TFA antagonizes the hypotensive response induced by systemic administration of urocortin in conscious rats. K41498 TFA undergoes radioiodination without loss of activity and serves for autoradiographic studies of native CRF2 receptors in rat brain and peripheral tissues .
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Cat. No.: HY-U00344A
CAS No.: 2572-61-4
Synonyms: (±)​-​Theodrenaline hydrochloride
Research Areas:  

Cardiovascular Disease

Theodrenaline hydrochloride is a cardiac stimulant, also acts as an anti-hypotensive agent together with Cafedrine.
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Cat. No.: HY-164704
CAS No.: 277333-45-6
Target:  

Neprilysin

Research Areas:  

Cardiovascular Disease

JA2 is an inhibitor of metalloendopeptidase 24.15 that can potentiate the hypotensive response to bradykinin in rat .
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Cat. No.: HY-B1800
CAS No.: 4201-22-3
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties .
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Cat. No.: HY-123179
CAS No.: 7195-27-9
Purity:  ≥99.0%
Target:  

Carbonic Anhydrase

Research Areas:  

Cardiovascular Disease

Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension .
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Cat. No.: HY-121653
CAS No.: 98206-10-1
Purity:  99.90%
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects .
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Cat. No.: HY-P1106
CAS No.: 434938-41-7
Target:  

CRFR

Research Areas:  

Cardiovascular Disease

K41498 is a highly selective CRF 2 receptor antagonist, with a Ki of 0.66 nM for human CRF2α receptor and a Ki of 0.62 nM for human CRF2β receptor. K41498 inhibits cAMP accumulation in cells expressing CRF2. K41498 antagonizes the hypotensive response induced by systemic administration of urocortin in conscious rats. K41498 undergoes radioiodination without loss of activity and serves for autoradiographic studies of native CRF2 receptors in rat brain and peripheral tissues .
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Cat. No.: HY-U00344
CAS No.: 13460-98-5
Synonyms: (±)​-​Theodrenaline
Research Areas:  

Cardiovascular Disease

Theodrenaline is a cardiac stimulant, also acts as an anti-hypotensive agent together with cafedrine.
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Cat. No.: HY-P1573
CAS No.: 123337-89-3
Synonyms: BNP-45, rat
Brain Natriuretic Peptide-45, rat (BNP-45, rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .
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Cat. No.: HY-N0068R
CAS No.: 126-17-0
Synonyms: Purapuridine (Standard); Solancarpidine (Standard); Solasodin (Standard)
Solasodine (Standard) is the analytical standard of Solasodine. This product is intended for research and analytical applications. Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .
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Cat. No.: HY-122215
CAS No.: 62774-96-3
Synonyms: N-696
Target:  

Adrenergic Receptor

Research Areas:  

Endocrinology

Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities. Tilisolol hydrochloride exerts its effects in canine coronary arteries by opening ATP-sensitive K+ channels. Tilisolol hydrochloride exhibits concentration-dependent relaxation in KCl-precontracted rat thoracic aorta. Tilisolol hydrochloride reduces diastolic blood pressure in a dose-dependent manner and slightly increases heart rate in spinal cord stimulated rats .
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Cat. No.: HY-130395
CAS No.: 135646-98-9
Research Areas:  

Endocrinology

15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent .
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Cat. No.: HY-132277
CAS No.: 1163135-96-3
Research Areas:  

Endocrinology

15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive .
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Cat. No.: HY-13711
CAS No.: 203918-14-3
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

S-1255 is an orally active and highly selective endothelin ETA receptor antagonist (Kd=0.39 nM). S-1255 blocks vasoconstriction and sustains hypotensive effects in hypertensive rats. S-1255 is promising for research of hypertension and cardiovascular disorders .
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Cat. No.: HY-169221
CAS No.: 612548-45-5
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Perindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection .
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Cat. No.: HY-B0584R
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester(Standard); AL6221(Standard); Flu-Ipr (Standard)
Research Areas:  

Endocrinology

Travoprost (Standard) is the analytical standard of Travoprost. This product is intended for research and analytical applications. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
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Cat. No.: HY-P3889
CAS No.: 51165-07-2
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (HY-P0201). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect .
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