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Cat. No.: HY-U00344A

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Theodrenaline hydrochloride

(Synonyms: (±)-Theodrenaline hydrochloride)

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Based on 1 Customer Validation

Theodrenaline hydrochloride is a cardiac stimulant, also acts as an anti-hypotensive agent together with Cafedrine.

For research use only. We do not sell to patients.

Purity: 99.67%
CAS No.: 2572-61-4
Formula: C₁₇H₂₂ClN₅O₅
Molecular Weight:411.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Theodrenaline hydrochloride Chemical Structure

CAS No.: 2572-61-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Theodrenaline hydrochloride is a cardiac stimulant, also acts as an anti-hypotensive agent together with Cafedrine.

All Phosphodiesterase (PDE) Isoforms :

In Vitro

Akrinor evokes a positive inotropic effect in human atrial trabeculae via stimulation of β-adrenoceptors (AR)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Akrinor^TM produces significant potentiation of FSK effects, conceivable by PDE-inhibition, only at very high, clinically irrelevant concentrations of 420 mg/L^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2572-61-4
Appearance Solid
Molecular Weight 411.84
Formula C₁₇H₂₂ClN₅O₅
Color Off-white to light yellow
SMILES

O=C(N1C)N(C)C2=C(N(CCNCC(C3=CC=C(O)C(O)=C3)O)C=N2)C1=O.[H]Cl
Synonyms

(±)-Theodrenaline hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (242.81 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4281 mL

12.1406 mL

24.2813 mL

5 mM

0.4856 mL

2.4281 mL

4.8563 mL

10 mM

0.2428 mL

1.2141 mL

2.4281 mL

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kloth B, et al. AkrinorTM, a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro. Front Pharmacol. 2017 May 23;8:272. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4281 mL	12.1406 mL	24.2813 mL	60.7032 mL
	5 mM	0.4856 mL	2.4281 mL	4.8563 mL	12.1406 mL
	10 mM	0.2428 mL	1.2141 mL	2.4281 mL	6.0703 mL
	15 mM	0.1619 mL	0.8094 mL	1.6188 mL	4.0469 mL
	20 mM	0.1214 mL	0.6070 mL	1.2141 mL	3.0352 mL
	25 mM	0.0971 mL	0.4856 mL	0.9713 mL	2.4281 mL
	30 mM	0.0809 mL	0.4047 mL	0.8094 mL	2.0234 mL
	40 mM	0.0607 mL	0.3035 mL	0.6070 mL	1.5176 mL
	50 mM	0.0486 mL	0.2428 mL	0.4856 mL	1.2141 mL
	60 mM	0.0405 mL	0.2023 mL	0.4047 mL	1.0117 mL
	80 mM	0.0304 mL	0.1518 mL	0.3035 mL	0.7588 mL
	100 mM	0.0243 mL	0.1214 mL	0.2428 mL	0.6070 mL

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100 mg

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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Theodrenaline hydrochloride

All Phosphodiesterase (PDE) Isoforms

Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

Theodrenaline hydrochloride Related Classifications

HY-U00344A Related Classifications