Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
subtilisin
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "subtilisin" in MCE Product Catalog:
Cat. No.: HY-P5062
CAS No.: 534615-50-4
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Cat. No.: HY-W141825
CAS No.: 20874-31-1
Cat. No.: HY-158825
CAS No.: 2252375-14-5
Synonyms: CIVI007 sodium
Target:
Research Areas:
Cepadacursen sodium is a liver-targeting antisense oligonucleotide (ASO), inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) protein synthesis. Cepadacursen sodium can be used for hypercholesterolemia research and the prevention of atherosclerotic cardiovascular disease (ASCVD).
Cat. No.: HY-112598
CAS No.: 1900686-46-5
Target:
Research Areas:
PF-06815345 is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 significantly decreases the PCSK9 level in vivo in mouse .
Cat. No.: HY-158827
CAS No.: 2604215-74-7
Target:
Research Areas:
AZD8233, a liver-targeting antisense oligonucleotide (ASO), inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) protein synthesis. AZD8233 increases the available LDL receptors by reducing PCSK9 levels, thereby clearing LDL from the blood and decreasing LDL-C levels.
Cat. No.: HY-153451
CAS No.: 2455423-94-4
Target:
Research Areas:
PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, KD <200 nM). PCSK9 is involved in cholesterol metabolism and regulates levels of low-density lipoprotein cholesterol (LDL-C) in the blood. PCSK9- in -15 can be used to study cholesterol-lowering and dyslipidemia .
Cat. No.: HY-N10702
Target:
Cat. No.: HY-P10215
Cat. No.: HY-159479
PfSUB1-IN-1 (compound 4c) is a plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1) Inhibitor (IC50: 15 nM). PfSUB1 is an antimalarial target. PfSUB1-IN-1 inhibits the growth of a genetically modified P. falciparum line expressing reduced levels of PfSUB1 13-fold more efficiently compared to a wild-type parasite line .
Cat. No.: HY-129407
CAS No.: 184901-82-4
Synonyms: Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II
Target:
Research Areas:
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.
Cat. No.: HY-P2951A
Target:
Research Areas:
Phenylalanine Ammonia-Lyase, Rhodotorula glutinis (EC 4.3.1.24) can be cleaved and inactivated by the proteases chymotrypsin, subtilisin, and trypsin.
Cat. No.: HY-P700617
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK6; SPC4; Prev. PACE4; Paired Basic Amino Acid Cleaving System 4; subtilisin-Like Proprotein Convertase 4; Alternative Protein PCSK6; subtilisin/Kexin-Like Protease PACE4; subtilisin-Like Protease; Proprotein Convertase subtilisin/Kexin Type 6; Paired
Species:
Human
Source:
E. coli
Cat. No.: HY-P700621
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK6; SPC4; Prev. PACE4; Paired Basic Amino Acid Cleaving System 4; subtilisin-Like Proprotein Convertase 4; Alternative Protein PCSK6; subtilisin/Kexin-Like Protease PACE4; subtilisin-Like Protease; Proprotein Convertase subtilisin/Kexin Type 6; Paired
Species:
Human
Source:
HEK293
Cat. No.: HY-101832R
CAS No.: 1629166-02-4
Target:
Research Areas:
SBC-110736 (Standard) is the analytical standard of SBC-110736 (HY-101832). This product is intended for research and analytical applications. SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1 .
Cat. No.: HY-P79228
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FURIN; subtilisin-Like Proprotein Convertase 1; Prev. PCSK3; Paired Basic Amino Acid Cleaving Enzyme (Furin, Membrane Associated Receptor Protein); Prev. PACE; Furin (Paired Basic Amino Acid Cleaving Enzyme); Prev. FUR; Proprotein Convertase subtilisin/Ke
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P71189
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Proprotein Convertase subtilisin/Kexin Type 9; Convertase subtilisin/Kexin Type 9 Preproprotein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-E71543
Target:
Research Areas:
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase (EC 3.1.3.87) participates in the methionine salvage pathway in Bacillus subtilis.In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and EC 5.3.2.5, 2,3-diketo-5-methylthiopentyl-1-phosphate enolase.
Cat. No.: HY-P70966
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Others
Source:
HEK293
Cat. No.: HY-P75958
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Rhesus Macaque
Source:
HEK293
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
