41 Results for "

Benzolactam

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "Benzolactam" in MCE Product Catalog:

Cat. No.: HY-P10768
CAS No.: 159427-08-4
Target:  

PACAP Receptor

Research Areas:  

Inflammation/Immunology

Ro 25-1553 is a selective VIP2 receptor (VPAC2 receptor) agonist. Ro 25-1553 exhibits bronchodilatory effects on tracheal smooth muscle contractions induced by nerve stimulation or Carbachol (HY-B1208). Ro 25-1553 produces a superimposed effect when combined with Formoterol and Salmeterol (HY-14302). Ro 25-1553 can be used for the study of bronchoconstriction .
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Cat. No.: HY-P2123A
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria .
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Cat. No.: HY-P1193
CAS No.: 129623-01-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

GR 82334 is a potent and specific reversible tachykinin NK1 receptor antagonist . GR 82334 inhibits substance P-induced sensitization by blocking SP NK1 receptors in naked mole-rats .
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Cat. No.: HY-P1209
CAS No.: 944111-22-2
Target:  

Melanocortin Receptor

Research Areas:  

Inflammation/Immunology

PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor .
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Cat. No.: HY-P2120
CAS No.: 79438-64-5
Target:  

Bacterial

Research Areas:  

Others

Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
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Cat. No.: HY-10957A
CAS No.: 169188-19-6
Synonyms: MK-0751 hydrochloride
Target:  

GHSR

Research Areas:  

Metabolic Disease

L-692429 (MK-0751) hydrochloride is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 hydrochloride binds to G protein-coupled receptor with a Ki of 63 nM .
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Cat. No.: HY-P1195A
Target:  

iGluR

Research Areas:  

Neurological Disease

PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
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Cat. No.: HY-P10135
CAS No.: 151308-34-8
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM .
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Cat. No.: HY-P1208A
Target:  

Melanocortin Receptor

Research Areas:  

Inflammation/Immunology

PG-931 TFA, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R(IC50=2.4 nM). PG-931 TFA can reverse haemorrhagic shock and prevent multiple organ damage in vivo .
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Cat. No.: HY-P5568
CAS No.: 152835-17-1
Synonyms: RP 71955
Target:  

HIV

Research Areas:  

Infection

RP 71955 is an antimicrobial peptide against HIV-1 .
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Cat. No.: HY-P2202
CAS No.: 140198-04-5
Target:  

Bacterial

Research Areas:  

Others

Desferriferribactin is a cyclic peptide containing a thirteen-membered ring. Desferriferribactin is a precursor of pyoverdins .
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Cat. No.: HY-P11232
CAS No.: 1969250-99-4
Research Areas:  

Infection

NAB815 is a specific inhibitor of the Stx2a (Kd = 0.01 μM)/TLR4 interaction. NAB815 inhibits the neutrophil/Stx2a interaction (IC50 = 0.057 μg/mL). NAB815 inhibits the formation of Stx2-containing extracellular vesicles (EVs) produced by leukocytes and platelets and reduces their toxic effects in cellular (Vero cells) and animal models (CD-1 mice). NAB815 reduces bacterial loads in the kidneys, urine, and bladders of Escherichia coli-infected mice. NAB815 is useful in the study of hemolytic uremic syndrome (HUS) .
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Cat. No.: HY-10957R
CAS No.: 145455-23-8
Synonyms: MK-0751 (Standard)
Research Areas:  

Metabolic Disease

L-692429 (Standard) is the analytical standard of L-692429 (HY-10957). This product is intended for research and analytical applications. L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 binds to G protein-coupled receptor with a Ki of 63 nM .
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Cat. No.: HY-P10768B
Target:  

PACAP Receptor

Research Areas:  

Inflammation/Immunology

Ro 25-1553 acetate is a selective VIP2 receptor (VPAC2 receptor) agonist. Ro 25-1553 acetate exhibits bronchodilatory effects on tracheal smooth muscle contractions induced by nerve stimulation or Carbachol (HY-B1208). Ro 25-1553 acetate produces a superimposed effect when combined with Formoterol and Salmeterol (HY-14302). Ro 25-1553 acetate can be used for the study of bronchoconstriction .
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Cat. No.: HY-P0267A
CAS No.: 1036322-26-5
Melanotan (MT)-II acetate is a melanocortin receptor agonist. Melanotan (MT)-II acetate activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II acetate reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II acetate improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II acetate induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II acetate increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II acetate can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .
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Cat. No.: HY-P2123S
Research Areas:  

Others

Colistin A-d7 TFA is the deuterium labeled Colistin A.
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Cat. No.: HY-P11596
CAS No.: 3107808-75-0
Target:  

Integrin

Research Areas:  

Cancer

NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .
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Cat. No.: HY-P11607
Target:  

Bacterial

Research Areas:  

Infection

CyLip-10 is a microbial-derived cyclic-lipid antimicrobial peptide. CyLip-10 has broad-spectrum antimicrobial efficacy, low hemolytic activity, and excellent stability. CyLip-10 can disrupt membrane integrity, inhibit biofilm formation and induce membrane permeabilization and bacterial cell death. CyLip-10 reduces bacterial load, promotes wound healing, and alleviates inflammatory responses in a mouse Methicillin (HY-121544)-resistant Staphylococcus aureus skin wound infection model. CyLip-10 can be used for the bacterial infection .
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Cat. No.: HY-P11676
CAS No.: 1814918-91-6
Synonyms: BRII-693; QPX9003
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Soralimixin (BRII-693), a Polymyxin derivative, is a next-generation intravenous (IV)-administered synthetic macrocyclic peptide antibiotic. Soralimixin can be used for the study of infections caused by drug-resistant Gram-negative pathogens .
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Cat. No.: HY-P2209
CAS No.: 53947-96-9
Synonyms: Daechuine S27; N-Demethylamphibine H
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca 2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .
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