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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
Cdkn1a
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "Cdkn1a" in MCE Product Catalog:
Cat. No.: HY-182744
LLQ-45 is a covalent p53 Y220C mutant protein agonist with an EC50 of 24.97 μM. LLQ-45 activates the anti-tumor function of p53 Y220C through covalent modification, restores its DNA-binding ability and enhances its thermal stability. LLQ-45 selectively inhibits the proliferation of p53 Y220C mutant tumor cells, suppresses cell growth and upregulates the expression of CDKN1A. LLQ-45 can be used in studies related to p53 Y220C mutant cancers [1].
Cat. No.: HY-184244
CAS No.: 3094094-17-1
Synonyms: CAS-13312-010
Target:
Research Areas:
CAS-010 (CAS-13312-010) is a potent and selective USP28 inhibitor with an IC50 of 2.2 nM against full-length USP28. CAS-010 acts as a ubiquitin-competitive inhibitor and shows higher selectivity over USP25 (IC50 = 51 nM) and other USP family members, disrupting the 53BP1-USP28 interaction and suppressing p53-dependent transcription of CDKN1A (p21), MDM2, and BAX. CAS-010 can be used for studying USP28-mediated DNA damage response and p53 signaling in cancer-related research [1].
Cat. No.: HY-P87164
Synonyms: CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; Cdkn1 antibody; Cdkn1a antibody; CDN1a_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1a antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1a (P21) antibody; CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; Cdkn1 antibody; Cdkn1a antibody; CDN1a_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1a antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1a (P21) antibody; Cyclin-dependent kinase inhibitor 1a (p21, Cip1) antibody; DNA Synthesis Inhibitor antibody; MDA-6 antibody; MDA6 antibody; Melanoma differentiation-associated protein 6 antibody; Melanoma differentiation-associated protein antibody; p21 antibody; P21 protein antibody; p21CIP1 antibody; p21Cip1/Waf1 antibody; p21WAF antibody; PIC1 antibody; SDI1 antibody; SLC12A9 antibody; WAF1 antibody; Wild type p53 activated fragment 1 (WAF1) antibody; Wild type p53 activated fragment 1 antibody; Wildtype p53-activated fragment 1 antibody;
Cat. No.: HY-P702746
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; Mental Retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (Cdkn1a)-Activa
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705853
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; Mental Retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (Cdkn1a)-Activa
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P74654
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; Mental Retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (Cdkn1a)-Activa
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P87028
Synonyms: KIAA1142 antibody; p21 activated kinase 4 antibody; p21 Cdc42/Rac1-actiated kinase 4 antibody; P21 protein (Cdc42/Rac) activated kinase 4 antibody; p21(Cdkn1a) activated kinase 4 antibody; p21-activated kinase 4 antibody; PAK 4 antibody; PAK-4 antibody; Pak4 antibody; PAK4_HUMAN antibody; KIAA1142 antibody; p21 activated kinase 4 antibody; p21 Cdc42/Rac1-actiated kinase 4 antibody; P21 protein (Cdc42/Rac) activated kinase 4 antibody; p21(Cdkn1a) activated kinase 4 antibody; p21-activated kinase 4 antibody; PAK 4 antibody; PAK-4 antibody; Pak4 antibody; PAK4_HUMAN antibody; Protein kinase related to S.cerevisiae STE20 effector for Cdc42Hs antibody; Serine threonine kinase PAK 4 antibody; Serine/threonine protein kinase PAK 4 antibody; Serine/threonine protein kinase PAK4 antibody; Serine/threonine-protein kinase PAK 4 antibody; EC 2.7.11.1 antibody; KIAA1264 antibody; MGC26232 antibody; p21 activated kinase 7 antibody; p21 protein (Cdc42/Rac)-activated kinase 7 antibody; p21(Cdkn1a) activated kinase 7 antibody; p21-activated kinase 5 antibody; p21-activated kinase 7 antibody; PAK 5 antibody; PAK 7 antibody; PAK-5 antibody; PAK-7 antibody; PAK5 antibody; PAK7 antibody; PAK7_HUMAN antibody; Protein kinase PAK5 antibody; Serine/threonine protein kinase PAK 7 antibody; Serine/threonine-protein kinase PAK 7 antibody; Cdkn1a activated kinase 6 antibody; EC 2.7.1.37 antibody; p21 activated protein kinase 6 antibody; p21 protein (Cdc42/Rac)-activated kinase 6 antibody; p21(Cdkn1a) activated kinase 6 antibody; p21-activated kinase 6 antibody; p21activated kinase 6 antibody; PAK 6 antibody; PAK-6 antibody; Pak6 antibody; PAK6_HUMAN antibody; Serine threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK6 antibody; Serine/threonine-protein kinase PAK 6 antibody;
Cat. No.: HY-P706080
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PAK5; P21-Activated Kinase 5; Prev. PAK7; PAK-5; KIAA1264; PAK-7; P21 Protein (Cdc42/Rac)-Activated Kinase 7; Serine/Threonine-Protein Kinase PAK 7; Serine/Threonine-Protein Kinase PAK 5; Serine/Threonine-Protein Kinase PAK7; P21(Cdkn1a)-Activated Kinase 7; P21Cdkn1a-Activated Kinase 7; P21 (RAC1) Activated Kinase 7; Protein Kinase PAK5; P21 (RAC1) Activated Kinase 5; P21-Activated Kinase 7
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701732
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAK6; P21(Cdkn1a)-Activated Kinase 6; P21 (RAC1) Activated Kinase 6; Non-Specific Serine/Threonine Protein Kinase; PAK5; P21-Activated Kinase 6; P21 Protein (Cdc42/Rac)-Activated Kinase 6; PAK-6; Serine/Threonine-Protein Kinase PAK 6; PAK-5
Species:
Human
Source:
E. coli
Cat. No.: HY-P72065
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PAK5; P21-Activated Kinase 5; Prev. PAK7; PAK-5; KIAA1264; PAK-7; P21 Protein (Cdc42/Rac)-Activated Kinase 7; Serine/Threonine-Protein Kinase PAK 7; Serine/Threonine-Protein Kinase PAK 5; Serine/Threonine-Protein Kinase PAK7; P21(Cdkn1a)-Activated Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701733
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAK6; P21(Cdkn1a)-Activated Kinase 6; P21 (RAC1) Activated Kinase 6; Non-Specific Serine/Threonine Protein Kinase; PAK5; P21-Activated Kinase 6; P21 Protein (Cdc42/Rac)-Activated Kinase 6; PAK-6; Serine/Threonine-Protein Kinase PAK 6; PAK-5
Species:
Human
Source:
E. coli
Cat. No.: HY-P702745
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK2; P21 (Cdkn1a)-Activated Kinase 2; P21 (RAC1) Activated Kinase 2; P21-Activated Kinase 2; PAK65; Gamma-PAK; P21 Protein (Cdc42/Rac)-Activated Kinase 2; PAK-2; S6/H4 Kinase; P58; PAKgamma; Non-Specific Serine/Threonine Protein Kinase; Serine/Threonine-
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702747
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAK4; Protein Kinase Related To S. Cerevisiae STE20, Effector For Cdc42Hs; P21 (RAC1) Activated Kinase 4; Non-Specific Serine/Threonine Protein Kinase; P21 Protein (Cdc42/Rac)-Activated Kinase 4; P21-Activated Kinase 4; Serine/Threonine-Protein Kinase PAK 4; KIAA1142; P21(Cdkn1a)-Activated Kinase 4; PAK-4
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
