667 Results for "

microbial

" in MedChemExpress (MCE) Product Catalog:
Products (667)

667 Results for "microbial" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-135897
CAS No.: 165393-06-6
Purity:  ≥98.0%
Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca 2+ channel opener and enhances Ca 2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: Human serum albumin
HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO -) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-Y0520
CAS No.: 97-65-4
Synonyms: Methylenesuccinic acid
Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-W050026
CAS No.: 28047-15-6
Synonyms: NSC 203800; Phenylacetyl-L-glutamine
Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-W015346
CAS No.: 501-97-3
Synonyms: 3-(4-Hydroxyphenyl)propionic acid
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N0658
CAS No.: 72-19-5
L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B0704
CAS No.: 123-99-9
Synonyms: Nonanedioic acid
Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-126490
CAS No.: 11006-33-0
Purity:  ≥95.0%
Phleomycin is a copper-dependent DNA damaging agent and antibiotic with antitumor activity. Phleomycin binds to DNA and produces ROS in the presence of reducing agents (such as dithiothreitol and glutathione), inducing single-strand and double-strand breaks in DNA. Phleomycin can induce cell apoptosis or mutation and is widely used in cancer inhibition, microbial genetic transformation (as a screening marker to improve fungal transformation efficiency) and DNA repair mechanism research .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N2406
CAS No.: 1078-61-1
Synonyms: 3,4-Dihydroxy-benzenepropanoic acid
Dihydrocaffeic acid is a microbial metabolite of flavonoids. Dihydrocaffeic acid scavenges intracellular ROS and increases nitric oxide synthase activity. Dihydrocaffeic acid reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Dihydrocaffeic acid has antioxidant, anti-inflammatory and anti-cartilage degradation activities .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W050026S
CAS No.: 1331909-01-3
Synonyms: NSC 203800-d5; Phenylacetyl-L-glutamine-d5
Phenylacetylglutamine-d5 (NSC 203800-d5) is the deuterium labeled Phenylacetylglutamine (HY-W050026). Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B0565
CAS No.: 7681-76-7
Target:  

Parasite Bacterial

Research Areas:  

Infection

Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-119500
CAS No.: 71678-03-0
Purity:  ≥98.0%
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus . Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N6624
CAS No.: 55084-08-7
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W013755
CAS No.: 117-84-0
Synonyms: DNOP; Di-n-octyl phthalate; Phthalic acid dioctyl ester
Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-D0256
CAS No.: 1937-37-7
Synonyms: Chlorazol Black E; Ferristatin II disodium; C.I. 30235
Direct Black 38 (Chlorazol Black E) is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-Y1139
CAS No.: 111-16-0
Synonyms: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid
Pimelic acid (Heptanedioic acid; 1,5-Pentanedicarboxylic acid) is a seven-carbon α,ω-dicarboxylic acid and a downstream product of fatty acid synthesis. Pimelic acid is a key precursor in biotin biosynthesis. Pimelic acid can be converted to pimelic acid-CoA by the BioW enzyme, thereby bypassing exogenous biotin requirements to support growth in various biotinytrophic bacteria and fungi, and reversing antibiotic-induced inhibition of biotin synthesis. Furthermore, Pimelic acid has been proposed as a highly specific biomarker for oxygen-induced retinopathy in mice. Pimelic acid can be used to study retinopathy of preterm infants, oxygen-induced retinopathy, and microbial biotin metabolism .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W014841
CAS No.: 532-94-5
Synonyms: N-Benzoylglycine sodium, 98%
Sodium hippurate, 98% is an orally active metabolite. Sodium hippurate, 98% can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Sodium hippurate, 98% decreases NRF2, MMP9 and leads to ROS accumulation. Sodium hippurate, 98% activates TGFβ/SMAD signaling. Sodium hippurate, 98% improves hyperuricemia and colitis. Sodium hippurate, 98% can also be used in cardiovascular disease research . .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B0172B
CAS No.: 1534-35-6
Synonyms: 3β-Hydroxy-5β-cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W012479
CAS No.: 153-94-6
Synonyms: D-Tryptophan
H-D-Trp-OH (D-Tryptophan) is the D-isomer of tryptophan, which is occasionally found in natural peptides, such as marine toxin peptides. H-D-Trp-OH can increase intestinal microbial diversity and counteract the inhibitory effect of allergic airway inflammation on intestinal microbial diversity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-157355
Synonyms: BHI
Brain Heart Infusion Broth (BHI) is a bacterial culture medium that can be used for microbial culture .
loading...
    loading...