840 Results for "

Essential

" in MedChemExpress (MCE) Product Catalog:
Products (840)

840 Results for "Essential" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-B2230
CAS No.: 499-44-5
Synonyms: β-Thujaplicin
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.
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9
9 Cited Publications
Cat. No.: HY-N0469
CAS No.: 56-87-1
L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation .
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7
7 Cited Publications
Cat. No.: HY-W010347
CAS No.: 6027-13-0
L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia .
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7
7 Cited Publications
Cat. No.: HY-B0430
CAS No.: 79-83-4
Synonyms: Pantothenate; Vitamin B5
D-Pantothenic acid (Pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism .
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7
7 Cited Publications
Cat. No.: HY-B0430A
CAS No.: 867-81-2
Synonyms: Sodium pantothenate; Vitamin B5 sodium
D-Pantothenic acid sodium (Sodium pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid sodium plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism .
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6
6 Cited Publications
Cat. No.: HY-128851
CAS No.: 85-61-0
Purity:  94.29%
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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6
6 Cited Publications
Cat. No.: HY-128851B
CAS No.: 55672-92-9
Purity:  99.46%
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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6
6 Cited Publications
Cat. No.: HY-128851A
CAS No.: 18439-24-2
Purity:  95.40%
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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6
6 Cited Publications
Cat. No.: HY-13560
CAS No.: 297730-17-7
Purity:  99.89%
Synonyms: VX-944
AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase). AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research .
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5
5 Cited Publications
Cat. No.: HY-109590S
CAS No.: 69254-37-1
Purity:  99.00%
Synonyms: Immunocytophyt-d8
Arachidonic acid-d8 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes .
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5
5 Cited Publications
Cat. No.: HY-N0486S9
CAS No.: 87828-86-2
L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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5
5 Cited Publications
Cat. No.: HY-141540
CAS No.: 1926-57-4
Purity:  98.01%
Research Areas:  

Others

Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers .
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5
5 Cited Publications
Cat. No.: HY-12903
CAS No.: 1377239-83-2
Purity:  98.46%
Synonyms: PBTZ169
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect .
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5
5 Cited Publications
Cat. No.: HY-N6810
CAS No.: 89-83-8
Thymol is a TRPA1 agonist. Thymol induces cancer cell apoptosis. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects .
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5
5 Cited Publications
Cat. No.: HY-W011727
CAS No.: 853645-22-4
Synonyms: Pyridoxal phosphate hydrate
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
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5
5 Cited Publications
Cat. No.: HY-W011727A
CAS No.: 41468-25-1
Synonyms: Pyridoxal phosphate monohydrate
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .
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5
5 Cited Publications
Cat. No.: HY-N0667
CAS No.: 70-47-3
Synonyms: (-)-Asparagine; Asn; Asparamide
L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
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5
5 Cited Publications
Cat. No.: HY-W017443
CAS No.: 5794-13-8
L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
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4
4 Cited Publications
Cat. No.: HY-N0832
CAS No.: 71-00-1
L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
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4
4 Cited Publications
Cat. No.: HY-N0230
CAS No.: 107-95-9
Synonyms: 2-Carboxyethylamine; 3-Aminopropanoic acid
β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
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